The Impact of Serum Uric Acid Levels on Hypertensive Disorders of Pregnancy in Advanced Maternal Age Women: A Retrospective Study from a Single Center in China

15 February 2024: Clinical Research

Li Luo ^12ADEFG* , Sulan Huang ^2ABCEF** , Zhijie Zhuang ^3BE* , Yeping Mo ^4BE* , Ning Guo ^2CE , Liangqing Ge ^12E*

DOI: 10.12659/MSM.942629

Med Sci Monit 2024; 30:e942629

Table 2 Influencing factors for SUA in the original population by univariate logistic regression analysis.

Covariate	HDP [OR (95% CI)]	P value
Age	0.94 (0.89, 0.99)	0.0275
Gravidity	0.85 (0.78, 0.93)	0.0002
Parity	0.75 (0.59, 0.95)	0.0193
BMI	1.17 (1.12, 1.22)
RDW	0.93 (0.86, 1.01)	0.0674
WBC	1.03 (0.97, 1.08)	0.3457
RBC	1.13 (0.94, 1.37)	0.1903
HB	1.04 (1.03, 1.05)
PLT	1.00 (1.00, 1.00)	0.4066
ALB	0.87 (0.84, 0.91)
ALT	1.00 (1.00, 1.01)	0.202
AST	1.01 (1.00, 1.01)	0.0103
BUN	1.36 (1.20, 1.55)
Creatinine	1.06 (1.05, 1.08)
Potassium	3.42 (2.06, 5.66)
TG	1.13 (1.02, 1.24)	0.0174
TC	1.14 (0.99, 1.32)	0.072
HDL	1.05 (0.73, 1.50)	0.7875
LDL	1.21 (0.96, 1.51)	0.1049
GLU	1.17 (1.05, 1.31)	0.0046
SUA	1.01 (1.01, 1.01)
ESR	1.03 (1.01, 1.04)	0.0001
SBP	1.17 (1.14, 1.19)
DBP	1.25 (1.21, 1.29)
Heart rate	1.02 (1.00, 1.03)	0.0073
Gestational week	0.99 (0.97, 1.02)	0.5223
GDM
Yes	1.0
No	1.59 (1.16, 2.18)	0.0038
Urine protein
Yes	1.0
No	1.89 (1.41, 2.54)
BMI – body mass index; WBC – white blood cell; RBC– red blood cell; Hb – haemoglobin; RDW – red blood cell distribution width; ALB – albumin; ALT – alanine transaminase; AST – aspartate transaminase;BUN – urea nitrogen; TC – total cholesterol; TG – triglyceride; HDL – high-density lipoprotein; LDL – low density lipoprotein; ESR – erythrocyte sedimentation rate; SBP – systolic blood pressure; DBP – diastolic blood pressure;GDM – gestational diabetes; HDP– hypertensive disorders of pregnancy.