15 February 2024 : Database Analysis
The Impact of Serum Uric Acid Levels on Hypertensive Disorders of Pregnancy in Advanced Maternal Age Women: A Retrospective Study from a Single Center in China
Li Luo12ADEFG, Sulan Huang2ABCEF*, Zhijie Zhuang3BE, Yeping Mo4BE, Ning Guo2CE, Liangqing Ge12EDOI: 10.12659/MSM.942629
Med Sci Monit 2024; 30:e942629
Table 2 Influencing factors for SUA in the original population by univariate logistic regression analysis.
| Covariate | HDP [OR (95% CI)] | P value |
|---|---|---|
| Age | 0.94 (0.89, 0.99) | 0.0275 |
| Gravidity | 0.85 (0.78, 0.93) | 0.0002 |
| Parity | 0.75 (0.59, 0.95) | 0.0193 |
| BMI | 1.17 (1.12, 1.22) | <0.0001 |
| RDW | 0.93 (0.86, 1.01) | 0.0674 |
| WBC | 1.03 (0.97, 1.08) | 0.3457 |
| RBC | 1.13 (0.94, 1.37) | 0.1903 |
| HB | 1.04 (1.03, 1.05) | <0.0001 |
| PLT | 1.00 (1.00, 1.00) | 0.4066 |
| ALB | 0.87 (0.84, 0.91) | <0.0001 |
| ALT | 1.00 (1.00, 1.01) | 0.202 |
| AST | 1.01 (1.00, 1.01) | 0.0103 |
| BUN | 1.36 (1.20, 1.55) | <0.0001 |
| Creatinine | 1.06 (1.05, 1.08) | <0.0001 |
| Potassium | 3.42 (2.06, 5.66) | <0.0001 |
| TG | 1.13 (1.02, 1.24) | 0.0174 |
| TC | 1.14 (0.99, 1.32) | 0.072 |
| HDL | 1.05 (0.73, 1.50) | 0.7875 |
| LDL | 1.21 (0.96, 1.51) | 0.1049 |
| GLU | 1.17 (1.05, 1.31) | 0.0046 |
| SUA | 1.01 (1.01, 1.01) | <0.0001 |
| ESR | 1.03 (1.01, 1.04) | 0.0001 |
| SBP | 1.17 (1.14, 1.19) | <0.0001 |
| DBP | 1.25 (1.21, 1.29) | <0.0001 |
| Heart rate | 1.02 (1.00, 1.03) | 0.0073 |
| Gestational week | 0.99 (0.97, 1.02) | 0.5223 |
| GDM | ||
| Yes | 1.0 | |
| No | 1.59 (1.16, 2.18) | 0.0038 |
| Urine protein | ||
| Yes | 1.0 | |
| No | 1.89 (1.41, 2.54) | <0.0001 |
| BMI – body mass index; WBC – white blood cell; RBC– red blood cell; Hb – haemoglobin; RDW – red blood cell distribution width; ALB – albumin; ALT – alanine transaminase; AST – aspartate transaminase;BUN – urea nitrogen; TC – total cholesterol; TG – triglyceride; HDL – high-density lipoprotein; LDL – low density lipoprotein; ESR – erythrocyte sedimentation rate; SBP – systolic blood pressure; DBP – diastolic blood pressure;GDM – gestational diabetes; HDP– hypertensive disorders of pregnancy. | ||