The Impact of Serum Uric Acid Levels on Hypertensive Disorders of Pregnancy in Advanced Maternal Age Women: A Retrospective Study from a Single Center in China

15 February 2024: Clinical Research

Li Luo ^12ADEFG* , Sulan Huang ^2ABCEF** , Zhijie Zhuang ^3BE* , Yeping Mo ^4BE* , Ning Guo ^2CE , Liangqing Ge ^12E*

DOI: 10.12659/MSM.942629

Med Sci Monit 2024; 30:e942629

Table 3 Influencing factors for SUA in the matched population by univariate logistics-regression analysis.

Covariate	HDP [OR (95% CI)]	P value
Age	0.92 (0.84, 1.01)	0.0722
Gravidity	0.84 (0.73, 0.97)	0.0144
Parity	0.69 (0.45, 1.05)	0.0841
BMI	1.24 (1.13, 1.35)
RDW	0.95 (0.85, 1.05)	0.3298
WBC	1.01 (0.93, 1.10)	0.802
RBC	0.99 (0.90, 1.09)	0.8596
HB	1.05 (1.03, 1.07)
PLT	1.00 (1.00, 1.01)	0.5333
ALB	0.87 (0.82, 0.93)
ALT	1.00 (0.99, 1.01)	0.9073
AST	1.00 (1.00, 1.01)	0.2269
BUN	1.88 (1.43, 2.45)
Creatinine	1.06 (1.04, 1.08)
Potassium	8.73 (3.35, 22.78)
TG	0.99 (0.85, 1.16)	0.9177
TC	0.88 (0.71, 1.10)	0.2789
HDL	0.95 (0.61, 1.49)	0.8199
LDL	0.87 (0.61, 1.22)	0.4123
GLU	1.21 (1.02, 1.44)	0.0273
SUA	1.01 (1.01, 1.01)
ESR	1.00 (0.98, 1.03)	0.6689
SBP	1.17 (1.12, 1.21)
DBP	1.24 (1.18, 1.30)
Heart rate	1.01 (0.99, 1.03)	0.1613
Gestational week	1.04 (1.00, 1.08)	0.0461
GDM
Yes	1.0
No6	1.76 (1.03, 3.04)	0.0403
Urine protein
Yes	1.0
No	1.56 (0.95, 2.58)	0.0815
BMI – body mass index; WBC – white blood cell; RBC – red blood cell; Hb – haemoglobin; RDW – red blood cell distribution width; ALB – albumin; ALT – alanine transaminase; AST – aspartate transaminase; BUN – urea nitrogen; TC – total cholesterol; TG – triglyceride; HDL – high-density lipoprotein; LDL – low density lipoprotein; ESR – erythrocyte sedimentation rate; SBP – systolic blood pressure; DBP – diastolic blood pressure; GDM– gestational diabetes; HDP – hypertensive disorders of pregnancy.