07 June 2024 : Clinical Research
Risk Factors for Postpartum Hemorrhage in Severe Pre-Eclampsia: A Retrospective Single-Centre Study of 1953 Cases
Yingzi Pan1ABCDE, Yuchuan Wang1ABCDE, Jiayan Miao1ABCDEF, Xiaohong Ji1BCEF, Chengqian Wu1ABC, Yixiao Wang1ABCDEF*, Hongjuan Ding1ABCDEFGDOI: 10.12659/MSM.943772
Med Sci Monit 2024; 30:e943772
Table 1 Basic characteristics between severe pre-eclampsia with postpartum hemorrhage and without postpartum hemorrhage.
| PPH (n=197) | Non-PPH (n=1756) | P | |
|---|---|---|---|
| Age (yrs), median (IQR) | 31.00 (6.50) | 30.00 (5.00) | 0.018* |
| BMI (kg/m), median (IQR) | 28.82 (5.35) | 28.67 (5.11) | 0.781 |
| Postpartum blood loss (ml), median (IQR) | 1085.00 (324.00) | 510.00 (160.00) | <0.001*** |
| Gestational week at delivery (weeks), median (IQR) | 36.71 (4.36) | 36.57 (4.39) | 0.090 |
| Diagnostic gestational weeks for sPE (weeks), median (IQR) | 36.43 (4.86) | 36.43 (4.86) | 0.081 |
| Interval between sPE diagnosis and delivery (weeks), median (IQR) | 0.00 (0.29) | 0.14 (0.29) | 0.141 |
| Systolic blood pressure (mmHg), median (IQR) | 160.00 (18.00) | 160.00 (17.00) | 0.030* |
| Diastolic blood pressure (mmHg), median (IQR) | 100.00 (13.00) | 101.00 (14.00) | 0.012* |
| Primipara, n (%) | 159 (80.71) | 1301 (74.09) | 0.042* |
| Previous miscarriages, n (%) | 88 (44.67) | 721 (41.06) | 0.329 |
| Modes of pregnancy, n (%) | |||
| Natural | 125 (63.45) | 1516 (86.33) | <0.001*** |
| Assisted reproduction | 72 (36.55) | 240 (13.67) | |
| Twin pregnancy, n (%) | 73 (37.06) | 195 (11.10) | <0.001*** |
| MCDA | 0 (0.00) | 3 (0.17) | 1.000 |
| DCDA | 73 (37.06) | 192 (10.93) | <0.001*** |
| Previous history of HDCP, n (%) | 3 (1.52) | 93 (5.30) | 0.020* |
| Family history of hypertension, n (%) | 9 (4.57) | 51 (2.90) | 0.199 |
| PPH – postpartum hemorrhage; BMI – body mass index; MCDA – monochorionic and double amniotic sacs; DCDA – double chorionic villus and double amniotic sacs; HDCP – hypertensive disorder complicating pregnancy. | |||