07 June 2024 : Clinical Research
Risk Factors for Postpartum Hemorrhage in Severe Pre-Eclampsia: A Retrospective Single-Centre Study of 1953 Cases
Yingzi Pan1ABCDE, Yuchuan Wang1ABCDE, Jiayan Miao1ABCDEF, Xiaohong Ji1BCEF, Chengqian Wu1ABC, Yixiao Wang1ABCDEF*, Hongjuan Ding1ABCDEFGDOI: 10.12659/MSM.943772
Med Sci Monit 2024; 30:e943772
Table 4 Basic characteristics of women with and without postpartum hemorrhage in the cesarean delivery and vaginal delivery groups.
| Cesarean section (n=1708) | Vaginal delivery (n=245) | |||||
|---|---|---|---|---|---|---|
| PPH (n=165) | Non-PPH (n=1543) | P | PPH (n=32) | Non-PPH (n=213) | P | |
| Age (yrs), median (IQR) | 31.00 (7.00) | 30.00 (5.00) | 0.007** | 30.00 (3.00) | 29.00 (4.50) | 0.945 |
| BMI (kg/m), median (IQR) | 29.05 (5.17) | 28.67 (5.17) | 0.471 | 27.65 (5.59) | 28.67 (4.60) | 0.549 |
| Postpartum blood loss, median (ml), (IQR) | 1107.00 (492.50) | 525.00 (158.00) | <0.001*** | 770.50 (276.50) | 409.00 (63.00) | <0.001*** |
| Gestational week at delivery (weeks), median (IQR) | 36.14 (3.79) | 36.14 (4.14) | 0.368 | 39.79 (2.11) | 39.29 (2.00) | 0.045* |
| Diagnostic gestational weeks for sPE (weeks), median (IQR) | 35.86 (4.71) | 36.00 (3.79) | 0.318 | 39.79 (2.54) | 39.14 (2.00) | 0.063 |
| Interval between sPE diagnosis and delivery (weeks), median (IQR) | 0.14 (0.29) | 0.14 (0.43) | 0.193 | 0.00 (0.00) | 0.00 (0.00) | 0.899 |
| Systolic blood pressure (mmHg), median (IQR) | 160.00 (16.00) | 160.00 (17.00) | 0.006** | 161.00 (12.50) | 162.00 (12.00) | 0.517 |
| Diastolic blood pressure (mmHg), median (IQR) | 100.00 (13.00) | 102.00 (13.00) | 0.017* | 99.00 (10.75) | 99.00 (11.00) | 0.739 |
| Primipara, n (%) | 131 (79.39) | 1254 (81.27) | 0.559 | 28 (87.50) | 178 (83.57) | 0.517 |
| Previous miscarriages, n (%) | 77 (46.67) | 568 (36.81) | 0.013* | 11 (34.38) | 65 (30.52) | 0.660 |
| Modes of pregnancy, n (%) | ||||||
| Natural | 96 (58.18) | 1311 (84.96) | <0.001*** | 29 (90.63) | 205 (96.24) | 0.330 |
| Assisted reproduction | 69 (41.82) | 232 (15.04) | 3 (9.38) | 8 (3.76) | ||
| Twin pregnancy, n (%) | 72 (43.64) | 191 (12.38) | <0.001*** | 1 (3.13) | 4 (1.88) | 1.000 |
| MCDA | 0 (0.00) | 2 (0.13) | 1.00 | 1 (3.13) | 1 (0.47) | 1.000 |
| DCDA | 72 (43.64) | 189 (12.25) | <0.001*** | 0 (0.00) | 3 (1.41) | 1.000 |
| Previous history of HDCP, n (%) | 2 (1.21) | 90 (5.83) | 0.012* | 1 (3.13) | 3 (1.41) | 1.000 |
| Family history of hypertension, n (%) | 8 (4.85) | 48 (3.11) | 0.234 | 1 (3.13) | 3 (1,41) | 1.000 |
| PPH – postpartum hemorrhage; BMI – body mass index; MCDA – monochorionic and double amniotic sacs; DCDA – double chorionic villus and double amniotic sacs; HDCP – hypertensive disorder complicating pregnancy. | ||||||