09 June 2024 : Clinical Research
Determining the Optimal Dosage of Dexmedetomidine for Smooth Emergence in Older Patients Undergoing Spinal Surgery: A Study of 44 Cases
Hyoeun Ahn1CDEF, Yun Jeong Chae1DEF, Gyu Bin Choi1BF, Min Gyu Lee1BF, Ji Young Yoo1ABCF*DOI: 10.12659/MSM.944427
Med Sci Monit 2024; 30:e944427
Table 2 Response rates observed and adjusted by PAVA approach.
| Dose (μg/kg) | Trials | Events | naiveProbability | pavaProbability |
|---|---|---|---|---|
| 0.15 | 3 | 2 | 0.6667 | 0.6667 |
| 0.20 | 3 | 2 | 0.6667 | 0.6667 |
| 0.25 | 8 | 7 | 0.8750 | 0.7692 |
| 0.30 | 5 | 3 | 0.6000 | 0.7692 |
| 0.35 | 21 | 20 | 0.9524 | 0.9523 |
| 0.40 | 4 | 4 | 1.0000 | 1.0000 |
| PAVA – pooled adjacent-violators algorithm. | ||||