20 February 2025 : Clinical Research
Predicting Cerebral Small Vessel Disease Burden Based on Thromboelastography in Patients with Acute Ischemic Stroke: A Pilot Study
Min Xia ACE 1*, DaiZong Wu BF 1, NengWei Yu CDF 2, GuoXiang Huang BF 1DOI: 10.12659/MSM.946303
Med Sci Monit 2025; 31:e946303
Table 3 Bidirectional stepwise logistic and ordinal regression analysis based on small vessel disease (SVD) burden scores and Fazekas scores.
| Parameter | Fazekas score | SVD burdens score | ||||||
|---|---|---|---|---|---|---|---|---|
| Score ≥2 | Ordinal score | Score ≥3 | Ordinal score | |||||
| OR (CI 95%) | P value | OR (CI 95%) | P value | OR (CI 95%) | P value | OR (CI 95%) | P value | |
| Female sex | 0.31 (0.11~0.80) | 0.021 | 0.53 (0.25~1.09) | 0.084 | 0.26 (0.08~0.75) | 0.016 | 0.33 (0.16~0.66) | 0.002 |
| Age (years) | 1.04 (1.01~1.09) | 0.020 | 1.06 (1.03~1.09) | <0.001 | 1.04 (1.00~1.08) | 0.058 | 1.05 (1.03~1.08) | <0.001 |
| Hypertension | 2.87 (1.21~7.25) | 0.020 | 2.38 (1.19~4.84) | 0.013 | 3.09 (1.17~9.07) | 0.029 | 3.10 (1.60~6.12) | <0.001 |
| History of stroke | 9.30 (2.51~46.59) | 0.002 | 8.10 (2.76~25.42) | <0.001 | 4.84 (1.45~17.13) | 0.011 | 5.58 (2.09~15.54) | <0.001 |
| MA (mm) | 1.20 (1.10~1.34) | <0.001 | 1.14 (1.06~1.22) | <0.001 | 1.24 (1.11~1.39) | <0.001 | 1.15 (1.08~1.23) | <0.001 |