Predicting Cerebral Small Vessel Disease Burden Based on Thromboelastography in Patients with Acute Ischemic Stroke: A Pilot Study

Min Xia; DaiZong Wu; NengWei Yu; GuoXiang Huang

doi:10.12659/MSM.946303

20 February 2025 : Clinical Research

Predicting Cerebral Small Vessel Disease Burden Based on Thromboelastography in Patients with Acute Ischemic Stroke: A Pilot Study

Min Xia^{ACE 1*}, DaiZong Wu^{BF 1}, NengWei Yu^{CDF 2}, GuoXiang Huang^{BF 1}

DOI: 10.12659/MSM.946303

Med Sci Monit 2025; 31:e946303

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Table 5 Comparison between the 2 models base on different predictor indexes for predicting small vessel disease (SVD) burden score (≥3) and Fazekas score (≥2). H-L.test.p is the P value for the Hosmer-Lemeshow test.

Model type	Cut_off	Specificity	Sensitivity	Youden Index	H-L.test.p
Predict Fazekas sore ≥2
ModelA	0.326	0.580	0.800	0.380	0.460
ModelB	0.374	0.739	0.764	0.503	0.358
ModelC	0.324	0.682	0.782	0.464	0.907
Predict SVD burden sore ≥3
ModelA	0.226	0.552	0.816	0.368	0.136
ModelB	0.263	0.686	0.684	0.370	0.900
ModelC	0.399	0.857	0.632	0.489	0.515

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Predicting Cerebral Small Vessel Disease Burden Based on Thromboelastography in Patients with Acute Ischemic Stroke: A Pilot Study

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