Gastrointestinal System Endoscopy and Pathological Findings in Non-Dialysis Chronic Kidney Disease: A Single-Center Study

04 March 2025 : Clinical Research

Mehmet Usta

^{ABEF 1*}, Alparslan Ersoy

^{AD 2}, Nazife Nur Özer Şensoy

^{B 1}, Suat Akgür

^{B 1}, Mustafa Özel

^{AD 3}, Yusuf Karaaslan

^{BD 4}, Hatice Ortac

^{C 5}

DOI: 10.12659/MSM.946516

Med Sci Monit 2025; 31:e946516

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Table 1 Comparison of laboratory parameters of both groups.

Variables	Total (n: 128)	Non-CKD group (n: 68)	CKD group (n: 60)	P value
Glucose (mg/dL)	102	96	115	0.170^*
Urea (mg/dL)	54.5	27	80	<0.001^*
Creatinine (mg/dL) (n: 110)	1.4	0.7	2.4	<0.001^*
eGFR ml/dk/1.73 m (n: 110)	44.6	98	28	<0.001^*
Uric acid (mg/dL)	5.8	5.2	6.2	0.069^*
Sodium (mmol/L)	139.1	139.8	138.7	0.124^#
Potassium (mmol/L)	4.5	4.3	4.6	0.007^#
Calcium (mg/dL)	8.9	9.5	8.9	<0.001^#
Phosphorus (mg/dL)	4.1	3.3	4.2	0.029^*
Total protein (g/dL)	62.9	71.4	59.8	<0.001^*
Total Cholesterol (mg/dL)	174	207	145	0.005^#
HDL (mg/dL) (n: 31)	48	56	38	<0.001^*
Triglyceride (mg/dL)	135	108	164	0.444^*
LDL (mg/dL)	113	117	105	0.270^*
AST (IU/L)	16.5	17	16	0.981^#
ALT (IU/L)	15	18.5	12	0.012^*
CRP (mg/L)	3.4	0.6	12	<0.001^*
Iron (μg/dl)	63.2	67.9	59.2	0.519^#
TIBC (μg/dl)	253	266	243	0.421^#
Ferritin (μg/L)	77	40.5	215	<0.001^*
Erythrocytes (10 μL)	4.2	4.7	3.5	<0.001^*
Hemoglobin (g/dL)	11.8	13.3	10.1	<0.001^*
Hematocrit (%)	36.1	40.2	30.5	<0.001^*
RDW (fL)	14.6	13.6	15.9	<0.001^*
Platelet (10 μ/L)	234	249.5	195.5	<0.001^*
MPV (fL)	10	9.8	10.6	0.003^*
Data are expressed as median values. eGFR – estimated glomerular filtration rate; HDL – high-density lipoprotein; LDL – low-density lipoprotein; AST – aspartate aminotransferase; ALT – alanine aminotransferase; CRP – C-reactive protein; TIBC – total iron binding capacity; RDW – red cell distribution; MPV – mean platelet volume. ^* Mann-Whitney U test, ^# independent paired-sample test.

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