05 April 2025 : Clinical Research
Hemoglobin-Albumin-Lymphocyte-Platelet Index and Risk of In-Hospital Mortality in 793 Adult Patients Hospitalized for Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Makbule Ozlem Akbay
ABCDEF 1*, Dilek Ernam AEF 1, Lale Sertcelik BCDF 1, Fatma Ozbaki BCDF 1
DOI: 10.12659/MSM.947098
Med Sci Monit 2025; 31:e947098
Table 5 Univariate and multivariate logistic regression analyses for in-hospital mortality risk.
| Variables | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | P value | |||
| LB | UB | LB | UB | |||||
| Age | 1.062 | 1.032 | 1.094 | 1.040 | 1.007 | 1.073 | ||
| Chronic heart failure+ atrial fibrillation | 2.248 | 1.296 | 3.900 | |||||
| Respiratory failure | 4.776 | 2.132 | 10.698 | 4.716 | 2.033 | 10.941 | ||
| Diabetes mellitus | 1.818 | 1.035 | 3.194 | |||||
| Atherosclerotic cardiovascular disease | 2.541 | 1.462 | 4.417 | 2.545 | 1.388 | 4.668 | ||
| WBC | 1.082 | 1.025 | 1.142 | |||||
| RBC | 0.508 | 0.341 | 0.757 | |||||
| Hemoglobin | 0.924 | 0.881 | 0.968 | |||||
| Hematocrit | 0.737 | 0.637 | 0.852 | |||||
| Lymphocyte count | 0.489 | 0.317 | 0.753 | |||||
| Neutrophil count | 1.144 | 1.074 | 1.219 | 1.126 | 1.049 | 1.208 | ||
| NLR | 1.042 | 1.018 | 1.068 | |||||
| PLR | 1.001 | 1.000 | 1.002 | 0.151 | ||||
| CRP | 1.011 | 1.007 | 1.015 | |||||
| Urea | 1.016 | 1.008 | 1.025 | |||||
| Albumin | 0.878 | 0.831 | 0.926 | 0.894 | 0.840 | 0.953 | ||
| HALP score | 0.576 | 0.438 | 0.758 | 0.758 | 0.586 | 0.980 | ||
| Logistic regression (Forward LR). WBC – white blood cell; RBC – red blood cell; NLR – neutrophil-to-lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; CRP – C-reactive protein; OR :– odds ratio; CI – confidence interval; LB – lower bound; UB – upper bound. | ||||||||