25 March 2025 : Clinical Research
Inflammatory Biomarkers in Smokers: Implications for Ligamentum Flavum Hypertrophy
Eyüp Çetin A 1*, Dilara Başgül Sagiri B 1, Eylem Burcu Kahraman Özlü D 1, Ezgi Akar BD 1, Eray Metin Güler
BD 2,3, Sarper Kocaoğlu BC 1, Hakan Beyaztaş BD 2,4, Emine Demir FG 5
DOI: 10.12659/MSM.947508
Med Sci Monit 2025; 31:e947508
Table 3 Diagnostic accuracy of IL-1β in differentiating smokers from non-smokers: ROC analysis results.
| AUC area under the curve | % 95 Confidence interval | p | |||
|---|---|---|---|---|---|
| IL1β | 0.828 | 0.721–0.935 | |||
| IL1β 510 Cut-off | 0.790 | 0.667–0.913 | |||
| IL1β | ≤510 | 26 | 7 | Sensitivity | 74.1% |
| >510 | 5 | 20 | Positive predictive value (PPV) | 80.0% | |
| Specificity | 83.9% | ||||
| Negative predictive value (NPV) | 78.8% | ||||
| AUC – area under the curve; CI – confidence interval; IL-1β – interleukin-1 beta; BMI – body mass index; PPV – positive predictive value; NPV – negative predictive value; SD – standard deviation. | |||||