25 March 2025 : Clinical Research
Inflammatory Biomarkers in Smokers: Implications for Ligamentum Flavum Hypertrophy
Eyüp Çetin A 1*, Dilara Başgül Sagiri B 1, Eylem Burcu Kahraman Özlü D 1, Ezgi Akar BD 1, Eray Metin Güler
BD 2,3, Sarper Kocaoğlu BC 1, Hakan Beyaztaş BD 2,4, Emine Demir FG 5
DOI: 10.12659/MSM.947508
Med Sci Monit 2025; 31:e947508
Table 4 Diagnostic performance of IL-6 levels in distinguishing smokers from non-smokers.
| AUC area under the curve | % 95 Confidence interval | p | |||
|---|---|---|---|---|---|
| IL6 | 0.730 | 0.598–0.862 | |||
| IL6 102.5 Cut-off | 0.744 | 0.613–0.875 | |||
| IL6 | ≤102.5 | 22 | 6 | Sensitivity | 77.8% |
| >102.5 | 9 | 21 | Positive predictive value (PPV) | 70.0% | |
| Specificity | 71.0% | ||||
| Negative predictive value (NPV) | 78.6% | ||||
| AUC – area under the curve; CI – confidence interval; IL-6 – interleukin-6; BMI – body mass ındex; PPV – positive predictive value; NPV – negative predictive value; SD – standard deviation. | |||||