Association Between Central Obesity and Membranous Nephropathy

12 July 2025 : Clinical Research

Daoyuan Lv^{BCDEFG 1,2}, Laping Chu^{BCDF 1,2}, Yuan Du^{BCDF 1,2}, Hongwei Jiang^{BCD 1,2}, Xilian Zhou^{BCD 1,2}, Yafen Yu^{AG 1,2*}

DOI: 10.12659/MSM.947570

Med Sci Monit 2025; 31:e947570

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Table 4 Logistic regression analysis of the associations of central obesity with massive proteinuria and severe podocyte injury in MN patients.

Central obesity
Models	Massive proteinuria	p	Models	Severe podocyte injury	p
	2.790 (1.327, 5.865)	0.007		3.753 (1.866, 7.547)	<0.001
	2.195 (1.020, 4.724)	0.044		2.997 (1.457, 6.166)	0.003
	2.012 (0.926, 4.370)	0.077		2.730 (1.302, 5.728)	0.008
	2.692 (1.060, 6.834)	0.037		2.724 (1.137, 6.523)	0.025
Adjusted variables: hypoalbuminemia, severe podocyte injury; hypoalbuminemia, hypercholesterolemia, hypertriglyceridemia, severe podocyte injury; sex, age, high normal MAP, hypoalbuminemia, hypercholesterolemia, hypertriglyceridemia, elevated HDL, elevated LDL, decreased eGFR, IgG deposit, IgA deposit, IgM deposit, C1q deposit, C3 deposit, presence of glomerular sclerosis, severe podocyte injury; massive proteinuria, hypoalbuminemia; massive proteinuria, hypoalbuminemia, hypercholesterolemia, hypertriglyceridemia; sex, age, high normal MAP, massive proteinuria, hypoalbuminemia, hypercholesteremia, hypertriglyceridemia, elevated HDL, elevated LDL, decreased eGFR, IgG deposit, IgA deposit, IgM deposit, C1q deposit, C3 deposit, presence of glomerular sclerosis.

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