01 April 2025 : Clinical Research
Association of Sex with Survival and Adverse Events in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors: A Single-Center Experience in Türkiye
Melike Yüksel Yavuz
ABCDEF 1*, Filiz Karapinar ABDE 2, Ceyda Anar DEF 3, Mehdi Ok CD 2, Sema Ertürk CD 4, Mine Gayaf DEF 2, Fatma Demirci Üçsular DEF 2, Gülru Polat DEF 2
DOI: 10.12659/MSM.947817
Med Sci Monit 2025; 31:e947817
Table 4 Mortality by sex (all patients and stage 4 disease patients).
| Number of deaths | % | Mean survival time | Log-rank (P) | |
|---|---|---|---|---|
| Men (n=88) | 19 | 21.6 | 79.9 | |
| Women (n=12) | 6 | 50.0 | 48.0 | |
| Men (n=69) | 14 | 20.3 | 84.5 | 0.087 |
| Women (n=10) | 5 | 50.0 | 48.9 | |
| Men (n=88) | 12 | 16.7 | 84.0 | |
| Women (n=11) | 6 | 54.5 | – | 0.471 |
| Men (n=88) | 0.800 | |||
| Low NLR (n=57) | 3 | 50.0 | 41.7 | |
| High NLR (n=31) | 3 | 50.0 | 52.6 | |
| Women (n=11) | 0.226 | |||
| Low NLR (n=6) | 10 | 17.5 | 86.6 | |
| High NLR (n=6) | 9 | 29.0 | 68.5 | |
| NLR – neutrophil-lymphocyte ratio. | ||||