10 July 2025 : Clinical Research
Quantitative Multi-Parameter MRI Evaluation of Hashimoto's Thyroiditis Changes After Dietary Interventions
Ning Dai
ACDEF 1, Qi-Hao Shi CEF 1, Long-Wei Zheng BDF 1, Xiao-Shan Huang BF 1,2, Shu-Feng Fan AEG 1,2*
DOI: 10.12659/MSM.947862
Med Sci Monit 2025; 31:e947862
Table 4 Comparison of laboratory and imaging indicators before and after 2 examinations in the intervention group.
| Parameter | Baseline data | After 6 months | Test statistic | P-value |
|---|---|---|---|---|
| TPOAb (KU/L) | 376.58±319.52 | 273.55±287.63 | −3.245** | 0.016 |
| TGAb (KU/L) | 219.06±572.54 | 198.80±567.59 | −2.455** | 0.024 |
| FT3 (pmol/L) | 4.51±0.45 | 4.26±0.29 | −1.771** | 0.077 |
| FT4 (pmol/L) | 15.42±1.79 | 15.67±1.58 | −0.673* | 0.509 |
| TSH (mIU/L) | 3.27±1.41 | 3.07±1.76 | 0.664* | 0.515 |
| Thyroid isthmus | 3.87±1.34 | 3.71±1.44 | 0.871* | 0.395 |
| Thyroid left lobe (mm) | 238.65±46.73 | 237.48±41.97 | 0.366* | 0.719 |
| Thyroid right lobe (mm) | 244.25±37.76 | 246.20±39.03 | −0.364* | 0.720 |
| T1WI RSI Mean | 0.98±0.18 | 0.99±0.16 | −0.404* | 0.691 |
| T2WI RSI Mean | 1.69±0.35 | 1.42±0.24 | 4.448* | <0.001 |
| FF Mean (%) | 7.90±1.98 | 8.31±2.05 | −2.350* | 0.030 |
| WF Mean (%) | 94.57±1.76 | 93.36±1.62 | 11.210* | <0.001 |
| ADC Mean (×10 mm/s) | 1.40±0.21 | 1.41±0.22 | −0.383* | 0.706 |
| * t-value; ** Z-value. BMI – body mass index; TPOAb – thyroid peroxidase antibody; TGAb – thyroglobulin antibody; FT3 – free triiodothyronine; FT4 – free thyroxine; TSH – thyroid-stimulating hormone; T1WI RSI – T1WI relative signal intensity; T2WI RSI – T2WI relative signal intensity; FF – fat fraction; WF – water fraction; ADC – apparent diffusion coefficient. | ||||