Development and Validation of a Predictive Nomogram for Early Postoperative Recurrence in Non-Small Cell Lung Cancer

13 July 2025 : Clinical Research

Zhi Liang^{ABCDEF 1}, Wei Lin^{ABCD 1}, Shipeng Fang^{BCDF 1}, Jianhao Zhang^{BCDF 1}, Jianhui Chen^{BCDF 1}, Feng Yuan^{A 2*}

DOI: 10.12659/MSM.948441

Med Sci Monit 2025; 31:e948441

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Table 2 Multivariate logistic regression analysis of factors associated with early postoperative recurrence.

Factors	β value	Standard error value	Wald value	OR value	95% CI for OR	P value
D-dimer (≥0.5 mg/L)	0.331	1.282	3.925	3.718	1.306~4.520	0.006
Pleural invasion	0.253	1.102	2.827	2.642	1.105~3.905	0.036
Lymphovascular invasion	0.295	1.024	3.482	3.194	1.117~4.251	0.015
Lymph node metastasis	0.208	0.997	2.373	2.088	1.360~2.988	0.028
T stage (T2/T3)	0.050	0.120	0.170	1.050	0.830~1.330	0.685
Tumor differentiation (Low)	0.150	0.160	0.880	1.160	0.850~1.590	0.386
CEA (≥5.0 ng/mL)	0.250	0.130	1.700	1.280	0.986~1.660	0.061
β – regression coefficient; OR – odds ratio; CI – confidence interval.

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