10 July 2025 : Clinical Research
Incremental Prognostic Value of Right and Left Atrial Volume Indices for Predicting Cardiovascular Outcomes in Atrial Fibrillation: A Cohort Study
Ferit Böyük
ABCDEF 1, Wenli Gu BD 2,3, Ching-Yan Zhu BD 3, Jingnan Zhang ACDF 2,3, Yan Chen DEF 4, Meizhen Wu BCE 2,3, Qingwen Ren BDF 2,3, Kai-Hang Yiu ABCDEF 2,3*
DOI: 10.12659/MSM.948798
Med Sci Monit 2025; 31:e948798
Table 1 Cut-off values according to specific outcomes.
| Variables | AUC | SE | Cut-off | Sensitivity | Specificity | 95% CI | P value |
|---|---|---|---|---|---|---|---|
| Age (years) | 0.750 | 0.024 | >74 | 64.44 | 78.42 | 0.705–0.790 | <0.001 |
| EDV (ml) | 0.572 | 0.029 | ≥79 | 38.33 | 78.01 | 0.523–0.619 | 0.013 |
| ESV (ml) | 0.504 | 0.029 | – | – | – | 0.455–0.553 | 0.8872 |
| LAVI (ml/m) | 0.762 | 0.024 | >51.88 | 64.44 | 82.57 | 0.718–0.802 | <0.001 |
| LAVI/RAVI | 0.545 | 0.028 | – | – | – | 0.496–0.593 | 0.114 |
| LVEF (%) | 0.623 | 0.026 | ≤60 | 77.22 | 50.21 | 0.575–0.670 | <0.001 |
| LVIDd (mm) | 0.569 | 0.029 | ≥4.45 | 49.44 | 66.39 | 0.520–0.617 | 0.017 |
| LVIDs (mm) | 0.512 | 0.029 | – | – | – | 0.463–0.561 | 0.670 |
| RAVI (ml/m) | 0.682 | 0.027 | >41.67 | 52.78 | 83.40 | 0.635–0.726 | <0.001 |
| The table presents the cut-off values for various variables in relation to specific outcomes. The area under the curve (AUC) is a measure of the accuracy of a diagnostic test, where higher values indicate better discrimination between conditions. The standard error (SE) provides an estimate of the variability of the AUC. The variables include EDV (End-Diastolic Volume), ESV (End-Systolic Volume), LA (Left Atrium), LAVI (Left Atrial Volume Index), LAVI/RAVI (Left Atrial Volume Index and Right Atrial Volume Index combined), LVEF (Left Ventricular Ejection Fraction), LVIDd (Left Ventricular Internal Dimension in Diastole), LVIDs (Left Ventricular Internal Dimension in Systole), and RAVI (Right Atrial Volume Index). | |||||||