10 July 2025 : Clinical Research
Incremental Prognostic Value of Right and Left Atrial Volume Indices for Predicting Cardiovascular Outcomes in Atrial Fibrillation: A Cohort Study
Ferit Böyük
ABCDEF 1, Wenli Gu BD 2,3, Ching-Yan Zhu BD 3, Jingnan Zhang ACDF 2,3, Yan Chen DEF 4, Meizhen Wu BCE 2,3, Qingwen Ren BDF 2,3, Kai-Hang Yiu ABCDEF 2,3*
DOI: 10.12659/MSM.948798
Med Sci Monit 2025; 31:e948798
Table 3 Cox analysis for death, stroke, and heart failure.
| Outcome | Model | Predictor | β | SE | 95% CI | HR | P value |
|---|---|---|---|---|---|---|---|
| Death | Without age and sex | LAVI/RAVI: One abnormal | 0.89 | 0.26 | 1.46–4.08 | 2.43 | 0.001 |
| LAVI/RAVI: Both abnormal | 1.80 | 59.90 | 3.85–9.58 | 6.07 | <0.001 | ||
| With age and sex | LAVI/RAVI: One abnormal | 0.68 | 0.27 | 1.17–3.31 | 1.96 | 0.011 | |
| LAVI/RAVI: Both abnormal | 1.48 | 0.25 | 2.71–7.08 | 4.38 | <0.001 | ||
| Sex (M vs F) | −0.04 | 0.20 | 0.65–1.40 | 0.96 | 0.821 | ||
| Age | 0.05 | 0.01 | 1.03–1.07 | 1.05 | <0.001 | ||
| Stroke | Without age And sex | LAVI/RAVI: One abnormal | 1.14 | 0.40 | 1.43–6.88 | 3.14 | 0.004 |
| LAVI/RAVI: Both abnormal | 1.75 | 0.38 | 2.75–12.0 | 5.74 | <0.001 | ||
| With age and sex | LAVI/RAVI: One abnormal | 0.94 | 0.40 | 1.17–5.63 | 2.56 | 0.019 | |
| LAVI/RAVI: Both abnormal | 1.36 | 0.39 | 1.82–8.41 | 3.91 | <0.001 | ||
| Sex (M vs F) | −0.26 | 0.29 | 0.44–1.37 | 0.77 | 0.382 | ||
| Age | 0.06 | 0.02 | 1.03–1.09 | 1.06 | <0.001 | ||
| Heart failure | Without age and sex | LAVI/RAVI: One abnormal | 1.39 | 0.30 | 2.25–7.13 | 4.00 | <0.001 |
| LAVI/RAVI: Both abnormal | 2.11 | 0.28 | 4.79–14.1 | 8.20 | <0.001 | ||
| With age and sex | LAVI/RAVI: One abnormal | 1.24 | 0.30 | 1.93–6.21 | 3.46 | <0.001 | |
| LAVI/RAVI: Both abnormal | 1.84 | 0.29 | 3.58–11.1 | 6.29 | <0.001 | ||
| Sex (M vs F) | 0.06 | 0.21 | 0.71–1.59 | 1.06 | 0.774 | ||
| Age | 0.03 | 0.01 | 1.01–1.05 | 1.03 | 0.002 | ||
| LAVI and RAVI are abbreviations for Left Atrial Volume Index and Right Atrial Volume Index, respectively. β indicates the Coefficient, and SE refers to the standard error. The hazard ratio is denoted as HR, and CI represents the confidence interval. The comparison between Male and Female is abbreviated as M vs F. Statistical significance is indicated by the value, with values less than 0.05 considered statistically significant. | |||||||