14 January 2013
The changing incidence of thyroid carcinoma in Shenyang, China before and after universal salt iodization
Wenwu DongABCDEF, Hao ZhangADEFG, Ping ZhangCD, Xuan LiBF, Liang HeBF, Zhihong WangBF, Yongfeng LiuADFDOI: 10.12659/MSM.883736
Med Sci Monit 2013; 19:49-53
Abstract
Background: An increase in the prevalence of thyroid disease has been found with increasing iodine intake, since universal salt iodization (USI) was instituted throughout China in 1996. The aim of this study was to analyze the incidence of thyroid carcinoma (TC) before and after USI in Shenyang, a city of northeastern China.
Material/Methods: The pathology reports were collected from patients with thyroid diseases who underwent surgery in the First Hospital of China Medical University from January 1, 1992 to December 31, 2009. The detection rate, the constituent ratio, the changes of sex, age, and concomitant thyroid diseases of each histological type of TC were analyzed.
Results: The detection rate of TC, papillary thyroid carcinoma (PTC), and medullary thyroid carcinoma (MTC) increased; that of follicular thyroid carcinoma (FTC) decreased; and that of undifferentiated thyroid carcinoma (UTC) showed no change after USI. The constituent ratio of PTC increased, that of FTC and UTC decreased, and that of MTC showed no change after USI. The mean age of female patients with TC decreased after USI. The incidences of PTC complicated with either nodular goiter or chronic lymphocytic thyroiditis increased after USI.
Conclusions: The detection rate of TC increased significantly, PTC predominated in the histological types of TC, and the mean age of female patients with TC decreased after USI. The patients with either nodular goiter or chronic lymphocytic thyroiditis under high iodine intake should be followed up.
Keywords: Iodine - pharmacology, Incidence, Dietary Supplements, China - epidemiology, Age Distribution, Sex Characteristics, Sodium Chloride, Dietary - pharmacology, Thyroid Neoplasms - epidemiology
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
15 Mar 2024 : Clinical Research
Evaluation of an Optimized Workflow for the Radiofrequency Catheter Ablation of Paroxysmal Atrial FibrillationMed Sci Monit In Press; DOI: 10.12659/MSM.943526
09 May 2024 : Review article
A Review of the Current Status of Disease-Modifying Therapies and Prevention of Alzheimer’s DiseaseMed Sci Monit In Press; DOI: 10.12659/MSM.945091
09 Apr 2024 : Clinical Research
Correlation between Thalamocortical Tract and Default Mode Network with Consciousness Levels in Hypoxic-Isc...Med Sci Monit In Press; DOI: 10.12659/MSM.943802
19 Apr 2024 : Clinical Research
Comparative Analysis of Postoperative Sagittal Balance in Expansive Open-Door Laminoplasty versus Laminecto...Med Sci Monit In Press; DOI: 10.12659/MSM.943057
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952