25 June 2015 : Clinical Research
Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy
Chunming ZhaoBC, Jiangping HouDEF, Shengxi WangDF, Rui JiangAGDOI: 10.12659/MSM.893403
Med Sci Monit 2015; 21:1839-1842
Abstract
BACKGROUND: Fetuin-A, a liver-derived glycoprotein, is correlated with diabetes. The aim of the present investigation was to evaluate serum and vitreous concentrations of fetuin-A in patients with diabetic retinopathy (DR).
MATERIAL AND METHODS: We randomly selected 224 diabetic patients and 68 control subjects for this study.
RESULTS: There were markedly higher serum and vitreous fetuin-A concentrations in proliferative diabetic retinopathy (PDR) patients than in the other three groups. NPDR patients exhibited elevated vitreous fetuin-A concentrations compared with patients without DR. However, no significant differences in serum fetuin-A concentrations were observed between NPDR patients and patients without DR. In addition, there were significantly lower concentrations of serum and vitreous fetuin-A in control subjects compared with the other three groups.
CONCLUSIONS: The occurrence and severity of DR is correlated with serum and vitreous fetuin-A concentrations.
Keywords: Diabetic Retinopathy - metabolism, Vitreous Body - metabolism, alpha-2-HS-Glycoprotein - metabolism
Editorial
01 September 2024 : Editorial
Editorial: Reasons for Increasing Global Concerns for the Spread of MpoxDOI: 10.12659/MSM.946343
Med Sci Monit 2024; 30:e946343
In Press
Review article
Pharmacological Strategies in Dermatomyositis: Current Treatments and Future DirectionsMed Sci Monit In Press; DOI: 10.12659/MSM.944564
Clinical Research
Effect of Hyaluronic Acid on Socket Healing After Lower Impacted Third Molar Tooth Extraction in 40 Dental ...Med Sci Monit In Press; DOI: 10.12659/MSM.945386
Review article
Cariprazine in Psychiatry: A Comprehensive Review of Efficacy, Safety, and Therapeutic PotentialMed Sci Monit In Press; DOI: 10.12659/MSM.945411
Clinical Research
Influenza Hemagglutinin Antibody Levels in the Elderly: Impact of Sex, Age, and Influenza/COVID-19 Vaccinat...Med Sci Monit In Press; DOI: 10.12659/MSM.945002
Most Viewed Current Articles
17 Jan 2024 : Review article 6,049,426
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research 1,832,003
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research 692,876
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
07 Jan 2022 : Meta-Analysis 257,339
Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Dise...DOI :10.12659/MSM.935074
Med Sci Monit 2022; 28:e935074