03 March 1997
Effects of the quantity of transfused blood and duration of haemodialysotherapy on potential possibility of HBV, HCV and CMV infections in chronically dialysed patients with secondary anaemia
Andrzej Steciwko, Beata Darska-Nykiel, Witold Pisarek, Robert Konarski, Beata Konarska, Andrzej JanuszewskiMed Sci Monit 1997; 3(2): CR183-189 :: ID: 500689
Abstract
The aim of the present study was to determine the relationship, if any of HBV, HCV and CMV infections in patients treated with repeated haemodialyses to the amount of transfused blood. Attention was focused on a seroconversion phenomenon in HBV and HCV positive people. The study included 53 patients (22 males, aged 26-63 years, mean 44.81 years and 31 females, aged 20-70 years, mean 46.06 years) treated with repeated haemodialyses because of end-stage renal failure. In our research we estimated the number of erythrocytes given to patients during haemodialysis sessions in their haemodialysis departments. From the study group 30 patients were qualified to enter the programme of the r-hEPO treatment (after satisfying the entry criteria i.e. exclusion of inflammatory processes, supplementation of iron and folic acid to reach the normal level, control of aluminium level). The patients started their r-hEPO treatment at different times from the beginning of haemodialysotherapy. In these 30 patients in whom the r-hEPO treatment was introduced at a later stage 75,600 ml of RBCs were transfused prior to the initiation of r-hEPO therapy. In 15 additional patients anaemia caused by renal failure and loss of blood during haemodialyses was successfully treated with the RBC transfusion. These 15 patients received 42,000 ml of RBCs (the mean amount was 2,800 ml per person). In 8 patients no transfusion was performed and 5 of those were treated with erythropoietin.
Results/Conclusions: 1.The risk of HBV and HCV infection increased with the amount of RBCs transfused in groups I and II. 2. In group III the number of HBV, HCV and CMV infections and coexisting infections did not differ from the number of infections in subgroup A of group I and subgroup E of group II. 3.The possibility of an HCV infection increased with the duration of the haemodialysotherapy in all groups. 4. The risk of coexisting infections increased with the duration of the haemodialysotherapy.
Keywords: Blood Transfusion, haemodialysotherap, HBV, HCV and CMV infections, secondary anaemia
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
11 Mar 2024 : Clinical Research
Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective AdditiveMed Sci Monit In Press; DOI: 10.12659/MSM.942946
12 Mar 2024 : Database Analysis
Risk Factors of Age-Related Macular Degeneration in a Population-Based Study: Results from SHIP-TREND-1 (St...Med Sci Monit In Press; DOI: 10.12659/MSM.943140
12 Mar 2024 : Clinical Research
Preoperative Blood Transfusion Requirements for Hemorrhoidal Severe Anemia: A Retrospective Study of 128 Pa...Med Sci Monit In Press; DOI: 10.12659/MSM.943126
12 Mar 2024 : Clinical Research
Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) and 3 (TIMP-3) as New Markers of Acute Kidney Injury Afte...Med Sci Monit In Press; DOI: 10.12659/MSM.943500
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952