01 November 1999
Concentration of selected cytokines of gastric mucosa in children with Helicobacter pylori infection
Elżbieta Maciorkowska, Maciej Kaczmarski, Andrzej KemonaMed Sci Monit 1999; 5(6): CR1140-1145 :: ID: 503165
Abstract
The concentrations of cytokines in homogenates of gastric mucosa were determined with ELISA and human antibodies (Endogen, USA) in 51 children complaining of abdominal pains. Morphological and histopathological assessment of gastric mucosa was performed in accordance with Sydney System in all the patients. The concentration of TNF-α, IL-2, IL-8 in gastric mucosa homogenates was statistically significantly higher than in control group. There were no statistically significant differences as to the concentration of IL-4 in mucosa. The concentration of IFN-γ in the studied group was statistically lower than in control subjects. High level of TFN-α, IL-2 and IL-8 in gastric mucosa homogenates infected with H. pylori in relation to children from control group might suggest that these cytokines play an important role in the pathogenesis of H. pylori infection.
Keywords: gastrointestinal mucosa, Cytokines, Helicobacter pylori
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
11 Mar 2024 : Clinical Research
Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective AdditiveMed Sci Monit In Press; DOI: 10.12659/MSM.942946
12 Mar 2024 : Database Analysis
Risk Factors of Age-Related Macular Degeneration in a Population-Based Study: Results from SHIP-TREND-1 (St...Med Sci Monit In Press; DOI: 10.12659/MSM.943140
12 Mar 2024 : Clinical Research
Preoperative Blood Transfusion Requirements for Hemorrhoidal Severe Anemia: A Retrospective Study of 128 Pa...Med Sci Monit In Press; DOI: 10.12659/MSM.943126
12 Mar 2024 : Clinical Research
Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) and 3 (TIMP-3) as New Markers of Acute Kidney Injury Afte...Med Sci Monit In Press; DOI: 10.12659/MSM.943500
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952