Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 November 2005

Serum retinol and total carotene concentrations in obese pre-school children.

Roseli Saccardo Sarni, Rosell Oselka Saccardo Sarni, Rejane Ramalho, Denise de Oliveira Schoeps, Cristiane Kochi, Priscila Catherino, Maria Carolina Pires Dias, Cristiane Ximenes Pessotti, Lilian de Queirós Mattoso, Fernando Basile Colugnati

Med Sci Monit 2005; 11(11): CR510-514 :: ID: 430363


Background: Obesity among pre-school children and its repercussions onadult life are growing problems, but there has been little research focusing on its relationship withthe deficiency of serum retinol and carotenoids in our region. Material/Methods: In a case-control study,a group of 46 preschool children, were matched by sex and age (23 obese and 23 non-obese subjects; averageage 5.74 and 5.76 years, respectively). Serum retinol and carotenoid levels were evaluated accordingto Underwood and Sauberlich. Other aspects evaluated included nutritional status using the weight/heightz-score (Obesity ZWH >/=2), serum levels of triglicerides (TG), total cholesterol (TC) and the VLDL-c,HDL-c, and LDL-c fractions, classified according to Kwiterovich. Results: Serum retinol insufficiencywas 18.2% vs. 6.7% (p=0.38) for cases and controls, respectively. Low carotenoid levels were found inthe obese in relation to the non-obese (82% vs. 26,6%, p=0,0054 and OR=12,4). No statistically significantdifference between the case and control groups was found for TC and cholesterol fractions, TG and retinol.The findings for the tested parameters were as follows: high TC (cases 30.4%, controls 21.7%; p=0.50),LDL-c (cases and controls 34.8%; p=0.50), low HDL-c (cases 17.4%, controls 26%; p=0.47), high TG (cases31.8%, controls 17.4%, p=0.65) and high VLDL-c (cases 21.7% and controls 8.7%; p=0.20). Conclusions:The association of obesity, hyperlipidemia and low serum level of carotenoids, which are essential toantioxidant protection, may be one of many factors predisposing obese children to a high risk of atherosclerosislater in life.

Keywords: Child, Case-Control Studies, Carotenoids - blood, Child, Preschool, Disease Susceptibility, Obesity - etiology, Vitamin A - blood

Add Comment 0 Comments

755 10


01 December 2023 : Editorial  

Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory Infections

Dinah V. Parums

DOI: 10.12659/MSM.943312

Med Sci Monit 2023; 29:e943312


In Press

01 Dec 2023 : Clinical Research  

Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Review article  

Decoding the Neurological Sequelae of General Anesthesia: A Review

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Clinical Research  

Enhanced Pain Relief and Muscle Growth in Individuals with Low Back Instability: The Impact of Blood Flow R...

Med Sci Monit In Press; DOI:  

29 Nov 2023 : Clinical Research  

Comparative Analysis of Intramedullary Nail versus Plate Fixation for Fibula Fracture in Supination Externa...

Med Sci Monit In Press; DOI:  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750