Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 August 2010

A newly-designed positioning system for simultaneous indocyanine green and fluorescein anterior segment angiography of the albino rabbit

Jianguo WuABCDEF, Xiaoxu ZhouAE, Long SuF, Song LinE, Guoling SunA, Luxia ChenA, Longli ZhangB, Xiaorong LiG

Med Sci Monit 2010; 16(8): BR246-249 :: ID: 881096

Abstract

Background: Simultaneous recording of vertical iris indocyanine green angiography (ICGA) and iris fluorescein sodium angiography (IFA) in albino rabbits.
Material/Methods: An easily adjusted control system was designed to position the CSLO scanning lens perpendicular to the surface of the iris. Twelve albino rabbits were randomly divided into 2 groups. Using 5 mg fluorescein sodium and 5 mg indocyanine green, iris angiograms (IA) of 6 albino rabbits were performed with application of the positioning system in Group A, and no positioning system in Group B. The time spending on vertical eye position and the effects of simultaneous IA were observed.
Results: With the use of the positioning system, the irises of rabbits quickly achieved the vertical site, averaging 37.50±8.17 s in Group A, and 408.33±58.79s in Group B. The difference was statistically significant, and the time saved averaged 370.83 s. Compared with the other methods of single-dye angiography, simultaneous digital angiography provided 2 kinds of full, dynamic videos of iris vessels in all albino rabbits. The emergence time of IFA and ICGA was 5–9 s, with an average time for ICGA of 6.4 s, and for IFA of 6.5 s. Except for leakage, the simultaneous ICGA and IFA appearance of this vascular pattern was the same as the single IFA described previously.
Conclusions: Simultaneous vertical IA with indocyanine green and fluorescein sodium is a potentially powerful technique that allows high-quality fluorescence imaging of the albino rabbit iris.

Keywords: Iris - radiography, Indocyanine Green - diagnostic use, Fluorescein Angiography - methods, Anterior Eye Segment - radiography, Albinism, Ocular - radiography, Rabbits, Time Factors

0 Comments

Editorial

01 October 2022 : Editorial  

Editorial: Rebound COVID-19 and Cessation of Antiviral Treatment for SARS-CoV-2 with Paxlovid and Molnupiravir

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.938532

Med Sci Monit 2022; 28:e938532

SARS-CoV-2/COVID-19

16 September 2022 : Review article  

Effects of Physiotherapy on Rehabilitation and Quality of Life in Patients Hospitalized for COVID-19: A Rev...

Med Sci Monit In Press; DOI: 10.12659/MSM.938141  

03 October 2022 : Clinical Research  

Effect of Vitamin D Concentration on Course of COVID-19

Med Sci Monit 2022; 28:e937741

In Press

03 Oct 2022 : Clinical Research  

Evaluation of Orthodontic Mini-Implant Placement in the Maxillary Anterior Alveolar Region in 15 Patients b...

Med Sci Monit In Press; DOI: 10.12659/MSM.937949  

30 Sep 2022 : Clinical Research  

Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938091  

30 Sep 2022 : Review article  

A Review of the Biological Mechanisms of Dexmedetomidine for Postoperative Neurocognitive Disorders

Med Sci Monit In Press; DOI: 10.12659/MSM.937862  

29 Sep 2022 : Animal Research  

Effect of Antilogous Platelet-Rich Plasma on the Revascularization of Rabbit Prefabricated Flap

Med Sci Monit In Press; DOI: 10.12659/MSM.937718  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750