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11 May 2015 : Meta-Analysis

[Retracted: 24 May 2016] Effects of Bariatric Surgery on Incidence of Obesity-Related Cancers: A Meta-Analysis

Xiang-wu YangABC, Peng-zhou LiACD, Li-yong ZhuCDEF, Shaihong ZhuAEFG

DOI: 10.12659/MSM.893553

Med Sci Monit 2015; 21:1350-1357

In the article entitled, "Effects of Bariatric Surgery on Incidence of Obesity-Related Cancers: A Meta-Analysis" which was published in Medical Science Monitor 2015;21: 1350-1357, sections in the text have been directly copied from a previously published article, entitled, "The Effects of Bariatric Surgery on Colorectal Cancer Risk: Systematic Review and Meta-Analysis", Sorena Afshar, Seamus B. Kelly, Keith Seymour, Jose Lara, Sean Woodcock, John C. Mathers  in Obesity Surgery 2014; 24(10):1793-1799. Thus owing to duplicity of text, the article is being retracted. Reference: 1. Xiang-wu Yang, Peng-zhou Li, Li-yong Zhu, Shaihong Zhu Effects of Bariatric Surgery on Incidence of Obesity-Related Cancers: A Meta-Analysis Medical Science Monitor 2015;21: 1350-1357 DOI: 10.12659/MSM.893553

Abstract

BACKGROUND: The aim of this meta-analysis was to investigate possible relationships between bariatric surgery and incidence of obesity-related cancers. Obesity is an established risk factor for obesity-related cancers but the effects of bariatric surgery on incidence of obesity-related cancers are uncertain.

MATERIAL AND METHODS: We searched 4 electronic databases to identify eligible studies: PubMed, Embase, Web of Science, and Google Scholar. Five observational studies were eligible and included in this meta-analysis. Random-effects or fixed-effects odds ratio (OR) and its corresponding 95% confidence interval (CI) were pooled.

RESULTS: Meta-analysis of these 5 observational studies revealed that bariatric surgery was associated with a significantly (p=0.0004) reduced incidence of obesity-related cancers (OR=0.43, 95%CI, 0.27–0.69) when compared with control individuals. Pooled estimated data showed that bariatric surgery is associated with a 24% lower colorectal cancer (CRC) risk. No publication bias was detected by Egger’s or Begg’s tests.

CONCLUSIONS: Although bariatric surgery may significantly reduce incidence of obesity-related cancers, considering the limitations of these included studies, these findings should be confirmed by further well-designed studies.

Keywords: Cohort Studies, Bariatric Surgery, Colorectal Neoplasms - prevention & control, Confounding Factors (Epidemiology), Data Accuracy, Disease Susceptibility, Incidence, Neoplasms - prevention & control, Obesity, Morbid - surgery, Observational Studies as Topic - statistics & numerical data, Publication Bias

Retraction note

Med Sci Monit 2016; 22:1751-1751     https://medscimonit.com/abstract/index/idArt/899711
 
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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750