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21 February 2015 : Review article  

Have Recent Investigations into Remission from Childhood Asthma Helped in Understanding the Pathogenesis of this Disease?

Piotr Z. BrewczyńskiABCDEFG, Andrzej BrodziakBCDE

DOI: 10.12659/MSM.893575

Med Sci Monit 2015; 21:570-575

Abstract

Studies show that a significant proportion of young people suffering from childhood onset asthma later recovered, usually in adolescence. In this article we argue that an understanding of the differences between children who recover from asthma and those who do not would contribute to increased understanding of the pathogenic mechanisms of the disease and could provide new clues about prevention and treatment. We note that some researchers have recently published results from these kinds of investigations. This paper reports results regarding genetic determinants, distorted mechanisms of inflammation, and mind/body relationships. We also try to integrate findings from these 3 areas to formulate general conclusions about the pathogenesis of asthma.

Keywords: Asthma - psychology, Child, Genetic Predisposition to Disease, Inflammation - immunology, Phenotype, Remission Induction

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Editorial

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Med Sci Monit 2024; 30:e946675

0:00

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750