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08 June 2024 : Clinical Research  

Machine Learning-Based Prediction of Helicobacter pylori Infection Study in Adults

Min Liu1ACE, Shiyu Liu2ABDG, Zhaolin Lu3DEF, Hu Chen4CD, Yuling Xu1BF, Xue Gong1CF, Guangxia Chen2AEG*

DOI: 10.12659/MSM.943666

Med Sci Monit 2024; 30:e943666



BACKGROUND: Helicobacter pylori has a high infection rate worldwide, and epidemiological study of H. pylori is important. Artificial intelligence has been widely used in the field of medical research and has become a hotspot in recent years. This paper proposed a prediction model for H. pylori infection based on machine learning in adults.

MATERIAL AND METHODS: Adult patients were selected as research participants, and information on 30 factors was collected. The chi-square test, mutual information, ReliefF, and information gain were used to screen the feature factors and establish 2 subsets. We constructed an H. pylori infection prediction model based on XGBoost and optimized the model using a grid search by analyzing the correlation between features. The performance of the model was assessed by comparing its accuracy, recall, precision, F1 score, and AUC with those of 4 other classical machine learning methods.

RESULTS: The model performed better on the part B subset than on the part A subset. Compared with the other 4 machine learning methods, the model had the highest accuracy, recall, F1 score, and AUC. SHAP was used to evaluate the importance of features in the model. It was found that H. pylori infection of family members, living in rural areas, poor washing hands before meals and after using the toilet were risk factors for H. pylori infection.

CONCLUSIONS: The model proposed in this paper is superior to other models in predicting H. pylori infection and can provide a scientific basis for identifying the population susceptible to H. pylori and preventing H. pylori infection.

Keywords: machine learning, Helicobacter pylori, Clinical Decision Rules

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01 June 2024 : Editorial  

Editorial: Concerns as Highly Pathogenic Avian Influenza (HPAI) Virus of the H5N1 Subtype is Identified in Dairy Cows and Other Mammals

Dinah V. Parums

DOI: 10.12659/MSM.945315

Med Sci Monit 2024; 30:e945315


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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750