01 March 2004
Med Sci Monit 2004; 10(3): CR96-101 :: ID: 11604
Background:The benefits of meditation are well documented, but the biochemical mechanisms have not been fully identified. One effect mechanism may be via influence on neurotransmitters.Material/Methods: Therefore, plasma melatonin and blood serotonin concentrations were measured before and after one hour of meditation in advanced male meditators (n=27, mean age 46 years). They were compared with a matched reference group (n=29, mean age 43 years) who rested for one hour. In the meditators, melatonin and serotonin from before and after three consecutive hours of meditation were also compared.Results: Initially, the median melatonin level was 4.9 pg/ml–1 in the meditators and 3.1 pg/ml–1 in the reference group (p<0.01). After one hour of practice, melatonin had decreased to a median of 3.4 pg/ml–1 in the meditators (p<0.0001), but was unchanged in the reference group. After three hours of meditation, melatonin had declined further in the meditators. After one hour of practice, serotonin concentrations decreased in both the meditators and the reference group (p<0.01).
Conclusions: The findings suggest that advanced meditators have higher melatonin levels than non-meditators. Melatonin decreases during long meditation, a finding the study does not explain. Serotonin declines after both one-hour meditation and rest, indicating that serotonin may be a marker of general rest and not meditation-specific relaxation.
Keywords: Meditation, Melatonin - blood, Neurotransmitter Agents - metabolism, Relaxation, Relaxation Techniques, Rest, Serotonin - blood, Time Factors, Meditation, Melatonin - blood, Neurotransmitter Agents - metabolism, Relaxation, Relaxation Therapy, Rest, Serotonin - blood, Time Factors
01 November 2023 : EditorialEditorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared
Med Sci Monit 2023; 29:e942960
28 Nov 2023 : Clinical ResearchImpact of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography on Therapeutic Decisions and ...
Med Sci Monit In Press; DOI: 10.12659/MSM.942122
28 Nov 2023 : Clinical ResearchLong-Term Outcomes of Decompression and Grafting in Acute Pathological Proximal Femur Fractures in Children...
Med Sci Monit In Press; DOI: 10.12659/MSM.943031
27 Nov 2023 : Clinical ResearchComparison of Outcomes from Emergency Admissions to a Major Trauma Center in Turkey of 1646 Elderly Patient...
Med Sci Monit In Press; DOI: 10.12659/MSM.942916
Most Viewed Current Articles
13 Nov 2021 : Clinical ResearchAcceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
14 Dec 2022 : Clinical ResearchPrevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels
Med Sci Monit 2022; 28:e937990
08 Mar 2022 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292