Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 2005

Effect of lower-body negative pressure on cerebral blood fl ow velocity during 21 days head-down tilt bed rest

Xi-Qing Sun, Yong-Jie Yao, Chang-Bin Yang, Shi-Zhong Jiang, Chang-Lin Jiang, Wen-Bin Liang

Med Sci Monit 2005; 11(1): CR1-5 :: ID: 13868

Abstract

Background: The purpose of this study was to investigate cerebral blood fl ow (CBF) velocity in humans during 21 days of head-down tilt (HDT) bed rest with and without lower-body negative pressure (LBNP). Material/Methods: Twelve healthy male volunteers were exposed to –6° HDT bed rest for 21 days. Six subjects received –30 mmHg LBNP sessions for 1 h per day from the 1[sup]st[/sup] to the 7[sup]th[/sup] day and from the 15[sup]th[/sup] to the 21st day of HDT, and six others served as controls. CBF velocity was measured by use of the transcranial Doppler technique in the right middle cerebral artery before and during HDT. Results: In the control group, mean and systolic CBF velocities decreased on day 1 of HDT compared with the pre-HDT value, and dropped further on day 3 of HDT, then remained signifi cantly below the pre-HDT baseline on days 7 and 10 of HDT, and reached a minimum value on day 21 of HDT. In the LBNP group, mean and systolic CBF velocities decreased signifi cantly on day 1 of HDT compared with the pre-HDT value, and remained lowered throughout HDT. Diastolic CBF showed no signifi cant change throughout HDT in both groups. There were no signifi cant differences in these parameters between the two groups. Conclusions: The results of this study suggest that CBF velocity is reduced during 21 days of HDT, and brief daily LBNP sessions used in the fi rst and last weeks of 21-day HDT bed rest does not improve CBF velocity.

Keywords: Head-Down Tilt - adverse effects, Bed Rest, Blood Pressure, Cerebrovascular Circulation, Head-Down Tilt - adverse effects, Lower Body Negative Pressure, Ultrasonography, Doppler, Transcranial, Weightlessness

0 Comments

Editorial

01 February 2023 : Editorial  

Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939580

Med Sci Monit 2023; 29:e939580

SARS-CoV-2/COVID-19

19 January 2023 : Clinical Research  

Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938892  

27 December 2022 : Clinical Research  

Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...

Med Sci Monit 2022; 28:e938926

10 December 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit 2022; 28:e938647

In Press

06 Feb 2023 : Clinical Research  

Double C-Arm Digital Subtraction Angiography Guidance During Transjugular Intrahepatic Portosystemic Shunt ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938912  

06 Feb 2023 : Review article  

Evolution of Hybrid Intelligence and Its Application in Evidence-Based Medicine: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.939366  

03 Feb 2023 : Clinical Research  

Treatment of Gingival Recession Defects with Pouch and Tunnel Technique Using Connective Tissue Graft and L...

Med Sci Monit In Press; DOI: 10.12659/MSM.938865  

02 Feb 2023 : Clinical Research  

Online Questionnaire-Based Study to Evaluate the Attitudes and Use of Rubber Dental Dams by Saudi Dental Pr...

Med Sci Monit In Press; DOI: 10.12659/MSM.938672  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750