Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 July 2005 : Extended abstract from EFAS 2011  

Effects of electrical stimulation on skin blood flow in controls and in andaround stage III and IV wounds in hairy and non hairy skin.

Jerrold Petrofsky, Ernie Schwab, Taiken Lo, Maria CĂșneo, James George, Jina Kim, Abdul Al-Malty

Med Sci Monit 2005; 11(7): CR309-316 :: ID: 16979


Background: While wounds heal more quickly when electrical stimulation(ES) is applied, few studies have examined blood flow (BF) in and around wounds during ES in controlswith no wounds compared to wounds in diabetic and non diabetic subjects. Material/Methods: Ten subjectswith stage III and IV wounds and 8 controls were subjected to 5 minutes of biphasic ES (20 milliamps,pulse width 250 usec). Before, during, and after, BF were measured by a Laser Doppler Imager. Results:For the control subjects, in the fingers, BF increased from 307 flux to 687 after 5 min of ES to onefinger but BF also increased to other fingers indicating a reflex increase in flow mediated by the sympatheticnervous system. For hairy skin, there was a 12% increase in BF with ES and only in the line directlybetween the stimulating electrodes. For the patients (either with or without Type 2 diabetes), stimulationin the hand, leg and foot all caused a large increase in BF during and for 5 minutes after stimulation.In patients, BF was high in the wound area before ES and increased by 53% during, and remained high afterstimulation was over. Conclusions: The results show that in wounds, where BF is high due to bradykininand cytokine release, the vasoconstrictor tone is not present and electrical stimulation causes a largeincrease in circulation which lasts after stimulation is over.

Keywords: Diabetes Mellitus, Type 2 - complications, Diabetes Mellitus, Type 2 - complications, Electric Stimulation Therapy, Foot - blood supply, Hair, Hand - blood supply, Laser-Doppler Flowmetry, Regional Blood Flow, Skin - injuries, Wound Healing

Add Comment 0 Comments

732 23


01 June 2023 : Editorial  

Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic Preparedness

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.941209

Med Sci Monit 2023; 29:e941209


In Press

05 Jun 2023 : Clinical Research  

Comparison of Texture and Color Enhancement Imaging with White Light Imaging in 52 Patients with Short-Segm...

Med Sci Monit In Press; DOI: 10.12659/MSM.940249  

05 Jun 2023 : Laboratory Research  

Comparison of Composite Resin (Duo-Shade) Shade Guide with Vita Ceramic Shades Before and After Chemical an...

Med Sci Monit In Press; DOI: 10.12659/MSM.940949  

02 Jun 2023 : Database Analysis  

The COVID-19 Crisis and the Incidence of Alcohol-Related Deaths in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.940904  

01 Jun 2023 : Clinical Research  

Root Canal Numbers and Configurations in 1080 Permanent Canine Teeth in 270 Saudi Subjects Using Cone-Beam ...

Med Sci Monit In Press; DOI: 10.12659/MSM.940472  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750