18 June 2002
Pathological somatosensory evoked potentials in patients with hypertension:a contribution to the study of the pathophysiology of juvenile essential hypertension.Pavel Varsik, Darina Buranová, Marek Baláz, Ivan Duris
Med Sci Monit 2002; 8(6): CR448-452 :: ID: 420809
BACKGROUND: The role of factors influencing the cerebral regulation ofblood pressure must be considered in the etiopathogenesis of essential hypertension The aim of our workwas to explore the possibilities for differentiating certain clinical, functional and electrophysiologicalsigns in young and adult hypertensives. This could help us to determine whether centrally active antihypertensivedrugs may be more suitable than others.MATERIAL/METHODS: We examined somatosensory evoked potentials(latencies of wave deflections and amplitudes) in two groups of patients with essential hypertension.The first group consisted of 25 hypertensive patients aged 20 to 30 years with onset before age 20 (n=25).The second group consisted of 40 hypertensive patients aged 40 to 60 years with onset after the age of30. The results were compared with those obtained from age-correlated healthy controls.RESULTS: The mostinteresting changes were observed in the amplitudes of somatosensory evoked potentials in the group ofjuvenile patients with hypertension. The decrease in the amplitude of all wave deflections was very compact,consistent, and statistically significant even after repeated examinations. This finding raises the possibilityof influence or damage to the peripheral afferentation of signals in juvenile patients, with hypertensionas an expression of the reactions of brainstem structures.CONCLUSIONS: Our results suggest that afferentimpulses and the reactivity of brainstem structures may play a role in the etiopathogenesis of hypertension.
Keywords: Evoked Potentials, Somatosensory, Hypertension
04 June 2022 : EditorialEditorial: Acute Hepatitis of Unknown Origin in Children. Is Autoimmunity at Play?
Med Sci Monit 2022; 28:e937371
27 June 2022 : Clinical ResearchShoulder Injury Related to Vaccine Administration (SIRVA) in 16 Patients Following COVID-19 Vaccination Who...
Med Sci Monit In Press; DOI: 10.12659/MSM.937430
04 June 2022 : Clinical ResearchScreening for SARS-CoV-2 Infection in Students at the Medical University of Warsaw, Poland Between November...
Med Sci Monit 2022; 28:e936962
30 May 2022 : Clinical ResearchEffects of Wearing Face Masks on Exercise Capacity and Ventilatory Anaerobic Threshold in Healthy Subjects ...
Med Sci Monit 2022; 28:e936069
30 Jun 2022 : Clinical ResearchAntioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty
Med Sci Monit In Press; DOI: 10.12659/MSM.936335
28 Jun 2022 : Meta-AnalysisUrodynamics in Early Diagnosis of Diabetic Bladder Dysfunction in Women: A Systematic Review and Meta-Analysis
Med Sci Monit In Press; DOI: 10.12659/MSM.937166
28 Jun 2022 : Clinical ResearchSerum Calprotectin – a NET Product – as a Biomarker of Disease Activity in Patients with Systemic Lupus Ery...
Med Sci Monit In Press; DOI: 10.12659/MSM.936534
Most Viewed Current Articles
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292
01 Nov 2020 : Review articleLong-Term Respiratory and Neurological Sequelae of COVID-19
Med Sci Monit 2020; 26:e928996