Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

11 March 2002

Clinical implications of acute myocardial infarction complicated by high grade atrioventricular block.

Francisco Ruiz-Ferrón, Mercedes Barranco-Ruiz, Humberto José Muńoz-Beltrán, Ziad Issa-Khozouz, Eduardo Aguayo de Hoyos, Manuel Ruiz-Bailén, Jesus Calatrava-López, Asuncion López-Martinez, Miguel Angel Díaz-Castellanos

Med Sci Monit 2002; 8(3): CR138-147 :: ID: 420913


BACKGROUND: The purpose of this study was to assess the incidence, clinicalcourse, prognosis and mean length of stay in acute myocardial infarction (AMI) complicated by high-gradeatrioventricular block (HAVB). MATERIAL/METHODS: A retrospective cohort study including all AMI patientslisted from January 1995 to September 2000 in the ARIAM multi-center register. Univariate analysis wascarried out to study the factors associated with the development of HAVB, the mortality rate, and themean length of stay, and multivariate logistic regression analysis to study whether HAVB is an independentpredictive variable for mortality or prolongation of stay. RESULTS: Of the 14,181 AMI patients includedin the register, 837 (5.9%) presented with HAVB, which was associated with age, female sex, increasedseverity, diabetes, inferior and Q-wave AMIs, and a higher peak creatine phosphokinase (CPK) level. TheHAVB patients developed more complications, required more diagnostic-therapeutic resources, and showedsignificantly higher mortality (p<0.0001) and increased mean length of stay (p<0.0001). The independent risk factors for HAVB were age, maximum peak CPK, inferior or combined localization of the AMI, Q-wave AMI, diabetes, a Killip and Kimball score > 1, and thrombolysis. HAVB was found to be an independent predictive variable for mortality and increased mean length of stay.
Conclusions: AMI patients with HAVB, despite thrombolytic treatment, are at risk for complications, mortality and longer mean admissions. Further study is needed on the outcome of a more active reperfusion policy, such as direct, rescue angioplasty etc.

Keywords: Heart Block, Logistic Models, Multivariate Analysis, Myocardial Infarction, Sex Factors, Time Factors

Add Comment 0 Comments

522 3


01 June 2023 : Editorial  

Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic Preparedness

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.941209

Med Sci Monit 2023; 29:e941209


In Press

08 Jun 2023 : Clinical Research  

Risk Factors for New Vertebral Compression Fracture After Percutaneous Vertebral Augmentation: A Retrospect...

Med Sci Monit In Press; DOI: 10.12659/MSM.940134  

08 Jun 2023 : Clinical Research  

A Nomogram for Identifying HR+/Her2- Breast Cancer Patients with Positive Sentinel Lymph Nodes and Omitted ...

Med Sci Monit In Press; DOI: 10.12659/MSM.940124  

08 Jun 2023 : Clinical Research  

Burden of COVID-19 on Mental Health of Resident Doctors in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.940208  

08 Jun 2023 : Clinical Research  

Risk Prediction for Rapidly Progressive Interstitial Lung Disease in Anti-MDA5-Positive Dermatomyositis: Th...

Med Sci Monit In Press; DOI: 10.12659/MSM.940251  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750