Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

22 February 2002

Cytomegalovirus infection and atherogenesis.

Lech Torliński, Marzena Wal, Joanna Bogaczyńska-Staniewicz, Andrzej Szkaradkiewicz

Med Sci Monit 2002; 8(2): CR104-107 :: ID: 420932


BACKGROUND: Experimental studies and clinical observations indicate theimportance of active CMV infection in the development of atherosclerosis. Our research constituted anattempt to evaluate the components of lipid metabolism (total cholesterol and its fractions, triglycerides)in children with active CMV infection. MATERIAL/METHODS: The research involved 45 children with activeprimary or secondary CMV infection. The diagnosis was established by measuring anti-CMV serum antibodies(IgM and IgG) using the Enzyme-Linked Fluorescent Assay (ELFA) technique, and by detecting CMV-DNA usingthe PCR technique. On the basis of diagnostic tests, the children were allocated to one of two groups.The first group of 15 children manifested primary active infection with CMV. The other group consistedof 30 children diagnosed with secondary active CMV infection. RESULTS: In the first group, the mean valuesof the serum lipid profile were as follows: total cholesterol--142 +/- 32.9 mg/dl; HDL-cholesterol:--23.4 +/- 8.6 mg/dl; LDL-cholesterol--97.8 +/- 30.9 mg/dl; triglycerides--83 +/- 15.5 mg/dl. In the secondgroup of children, the mean values of serum lipid profile were as follows: total cholesterol-- 142.5+/- 44.2 mg/dl; HDL-cholesterol--21.4 +/- 10.8 mg/dl, LDL-cholesterol--87.1 +/- 35.3 mg/dl; triglycerides--101.7+/- 31.2 mg/dl. In all these children, the values of total cholesterol, LDL-cholesterol, and triglyceridesconformed to published norms, while HDL-cholesterol was significantly below normal. CONCLUSIONS: Theresults we obtained point to dyslipidemia in the course of active CMV infection, which may be of pathogeneticsignificance at any stage of atherogenesis.

Keywords: Arteriosclerosis, Child, Child, Preschool, Cholesterol, Triglycerides

Add Comment 0 Comments


01 April 2024 : Editorial  

Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance

Dinah V. Parums

DOI: 10.12659/MSM.944600

Med Sci Monit 2024; 30:e944600


In Press

05 Apr 2024 : Clinical Research  

Comparative Analysis of Transoral Endoscopic Parathyroidectomy Vestibular Approach and Focused Open Surgery...

Med Sci Monit In Press; DOI: 10.12659/MSM.944128  


05 Mar 2024 : Clinical Research  

Muscular Function Recovery from General Anesthesia in 132 Patients Undergoing Surgery with Acceleromyograph...

Med Sci Monit In Press; DOI: 10.12659/MSM.942780  

05 Mar 2024 : Clinical Research  

Effects of Thermal Insulation on Recovery and Comfort of Patients Undergoing Holmium Laser Lithotripsy

Med Sci Monit In Press; DOI: 10.12659/MSM.942836  

05 Mar 2024 : Clinical Research  

Role of Critical Shoulder Angle in Degenerative Type Rotator Cuff Tears: A Turkish Cohort Study

Med Sci Monit In Press; DOI: 10.12659/MSM.943703  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750