Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 2001

Effect of scalp infiltration with lidocaine on the circulatory response tocraniotomy.

Cezary Pakulski, Rafał Nowicki, Beata Badowicz, Piotr Bąk, Krzysztof Mikulski, Beata Wojnarska

Med Sci Monit 2001; 7(4): CR725-728 :: ID: 421079


BACKGROUND: The purpose of the present study was to evaluate the influenceof infiltration anesthesia of the projected line of incision in the skin of head on the hemodynamic responseof the circulatory system, and the essential dose of opioids in 100 patients who underwent craniotomy.
MATERIAL AND METHODS: The patients were divided into 4 groups: IA - brain tumors, no infiltration anesthesia;IB - cerebral aneurysms, no infiltration anesthesia; IIA - brain tumors + infiltration anesthesia; IIB- cerebral aneurysms + infiltration anesthesia. In the patients from groups IIA and IIB, the projectedline of skin incision was injected with a 1% lidocaine solution (9.94+/-1.95 ml) five minutes beforecommencing surgery.
RESULTS: No statistically significant differences were found between the variousgroups in regards to their weight, the time between infusion of the first dose of fentanyl and skin incision,the mean heart rates at time points T1 (prior to induction of anesthesia), T2 (prior to skin incision)or T3 (after skin incision), or mean arterial pressure values (MAP) at time points T1 or T2. A significantincrease in MAP values (P<0.05) caused by skin incision was recorded in groups IA (from 95.2±9.85 to 119±10.6 mmHg) and IB (from 88.4±11.5 to 100.3±11.4 mmHg). In group IIA, MAP increased insignificantly, while in group IIB the MAP values did not change.
CONCLUSIONS: Infiltration anesthesia of the projected line of skin incision in the head enabled maintenance of stability in the circulatory system and lower doses of opioids administered before commencing surgery

Keywords: neuroanesthesia, skin incision, skin incision, Lidocaine

Add Comment 0 Comments


01 February 2024 : Editorial  

Editorial: Global Health Concerns as Vaccine-Preventable Infections Including SARS-CoV-2 (JN.1), Influenza, Respiratory Syncytial Virus (RSV), and Measles Continue to Rise

Dinah V. Parums

DOI: 10.12659/MSM.943911

Med Sci Monit 2024; 30:e943911


In Press

28 Dec 2023 : Clinical Research  

Prognostic Assessment of Colorectal Cancer Patients after Laparoscopic Surgery: A Comprehensive Evaluation ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942658  


05 Jan 2024 : Clinical Research  

Effectiveness of Glutamine Oral Care in Reducing Oral Mucositis and Improving Oral Health After Neurosurger...

Med Sci Monit In Press; DOI: 10.12659/MSM.942585  

02 Jan 2024 : Clinical Research  

Urinary Concentration of Renal Biomarkers in Healthy Term Neonates: Gender Differences in GST-pi Excretion

Med Sci Monit In Press; DOI: 10.12659/MSM.942819  

29 Dec 2023 : Clinical Research  

Performance of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) in Chinese Population with Prima...

Med Sci Monit In Press; DOI: 10.12659/MSM.942747  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750