Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 September 2005

Systemic Lupus Erythematosus (SLE) in Italy: an Italian prevalence study basedon a two-step strategy in an area of Florence (Scandicci-Le Signe).

Maurizio Benucci, Angela Del Rosso, Francesca Li Gobbi, Mariangela Manfredi, Marco Matucci Cerinic, Carlo Salvarani

Med Sci Monit 2005; 11(9): CR420-425 :: ID: 428449


Background: The goal was to ascertain the prevalence of SLE in the populationover18 years of age in the Scandicci-Le Signe area of Florence, Italy, based on the records of generalpractitioners (GPs). Material/Methods: Twenty GPs screened 32,521 patients by administering the LupusScreening Questionnaire (LQS) and found 30 patients with suspected or definite diagnosis of SLE. To confirmthe diagnoses the patients were referred to a rheumatologist who conducted routine examinations and assessedantinuclear antibodies and SLE activity (ECLAM score). Results: Total population >18 years of age inthe three municipalities was 71,204 persons, with 42,474 in Scandicci, 15,368 in Lastra a Signa, and13,362 in Signa. In 23/30 patients diagnosed with SLE the diagnosis was confirmed. Eleven of the 23 SLEpatients were from Scandicci and 6 each from Lastra a Signa and Signa. An overall estimated prevalenceof SLE of 71/100,000 (1/1408; 95% CI=49, 92) was found in the total population of the three municipalities.Scandicci (95% CI=42, 121) had a rate of 81/100.000, while Lastra a Signa (95% CI=32, 92) and Signa (95%CI=36, 94) had estimated rates of 62/100,000 and 65/100,000, respectively. Medium ECLAM score was 4.68+/-1.81SD. Conclusions: This is the first epidemiological study on SLE prevalence in Italy. The prevalence andpoint prevalence are similar to other European studies. The LQS was also confirmed as an easy and reliabletool to assess SLE diagnosis in the Italian population.

Keywords: Family Practice, Italy - epidemiology, Lupus Erythematosus, Systemic - epidemiology, Mass Screening, Questionnaires, Rheumatology

Add Comment 0 Comments


01 May 2024 : Editorial  

Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)

Dinah V. Parums

DOI: 10.12659/MSM.944927

Med Sci Monit 2024; 30:e944927

In Press

16 Mar 2024 : Clinical Research  

Diagnostic Efficiency of ACR-TIRADS Score for Differentiating Benign and Malignant Thyroid Nodules of Vario...

Med Sci Monit In Press; DOI: 10.12659/MSM.943228  


08 May 2024 : Clinical Research  

Effect of Individualized PEEP Guided by Driving Pressure on Diaphragm Function in Patients Undergoing Lapar...

Med Sci Monit In Press; DOI: 10.12659/MSM.944022  


21 Mar 2024 : Clinical Research  

Impact of Serum Vitamin D, B6, and B12 and Cognitive Functions on Quality of Life in Peri- and Postmenopaus...

Med Sci Monit In Press; DOI: 10.12659/MSM.943249  

17 Mar 2024 : Clinical Research  

Protective Role of TRPC3 Gene Polymorphism (rs10518289) in Obstructive Sleep Apnea Hypopnea Syndrome Among ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942667  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750