01 March 2006
Chronic black tea administration protects plasma proteins, plasma, liver andkidney lipids against oxidation.
Esma Sürmen-Gür, Tuna Gülten, Zehra Serdar, Mukaddes ColakogullariMed Sci Monit 2006; 12(3): BR102-105 :: ID: 447103
Abstract
Background: Black tea is known to have protective effects against plasmalipid and lipoprotein oxidation, but its influence on lipid peroxidation in tissue has been less studied.The effect of oral black tea consumption on protein oxidation has also not been demonstrated. The presentstudy investigated the antioxidant effects of oral black tea consumption. Material/Methods: Male Sprague-Dawleyrats were fed a regular murine chow diet. The controls were supplied with water ad libitum, while theblack tea group received aqueous black tea extract as the sole source of liquids. At the end of the ten-weekexperimental period, intestinal brush border, liver and kidney reduced-glutathione concentrations wereevaluated as an index of cellular antioxidant defence. Plasma and tissue malondialdehyde concentrationsand plasma protein carbonyl content were measured to evaluate lipid peroxidation and protein oxidation,respectively. Results: The plasma malondialdehyde and protein carbonyl contents of rats consuming theblack tea were significantly less than in controls. Similarly, liver and kidney malondialdehyde concentrationswere significantly lower in the experimental group, while jejunoileal mucosa were not affected. Ten weeksof black tea administration caused significantly higher reduced-glutathione levels in the kidneys ofblack tea-administered rats, and a significant negative correlation was observed between kidney malondialdehydeand glutathione concentrations. Conclusions: These findings provide evidence that long term black teasupplementation is capable of protecting both plasma proteins and plasma lipids from oxidative injury,and demonstrate that chronic black tea administration protects both liver and kidney tissues - but notthe jejunoileal mucosa - against oxidation.
Keywords: Thiobarbituric Acid Reactive Substances - analysis, Tea - chemistry, Reference Standards, Random Allocation, Plant Extracts - pharmacology, Malondialdehyde - blood, Antioxidants - pharmacology, Liver - drug effects, Lipids - blood, Lipid Peroxidation - drug effects, Kidney - drug effects, Glutathione - analysis, Blood Proteins - drug effects, Administration, Oral
718 5
Editorial
01 December 2023 : Editorial
Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory InfectionsDOI: 10.12659/MSM.943312
Med Sci Monit 2023; 29:e943312
In Press
08 Dec 2023 : Clinical Research
Association Between Influenza Vaccine Uptake and Health Awareness: A Cross-Sectional Questionnaire-Based St...Med Sci Monit In Press; DOI:
04 Dec 2023 : Animal Research
Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mech...Med Sci Monit In Press; DOI:
01 Dec 2023 : Clinical Research
Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...Med Sci Monit In Press; DOI:
30 Nov 2023 : Review article
Decoding the Neurological Sequelae of General Anesthesia: A ReviewMed Sci Monit In Press; DOI:
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292