Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 March 2006

Chronic black tea administration protects plasma proteins, plasma, liver andkidney lipids against oxidation.

Esma Sürmen-Gür, Tuna Gülten, Zehra Serdar, Mukaddes Colakogullari

Med Sci Monit 2006; 12(3): BR102-105 :: ID: 447103


Background: Black tea is known to have protective effects against plasmalipid and lipoprotein oxidation, but its influence on lipid peroxidation in tissue has been less studied.The effect of oral black tea consumption on protein oxidation has also not been demonstrated. The presentstudy investigated the antioxidant effects of oral black tea consumption. Material/Methods: Male Sprague-Dawleyrats were fed a regular murine chow diet. The controls were supplied with water ad libitum, while theblack tea group received aqueous black tea extract as the sole source of liquids. At the end of the ten-weekexperimental period, intestinal brush border, liver and kidney reduced-glutathione concentrations wereevaluated as an index of cellular antioxidant defence. Plasma and tissue malondialdehyde concentrationsand plasma protein carbonyl content were measured to evaluate lipid peroxidation and protein oxidation,respectively. Results: The plasma malondialdehyde and protein carbonyl contents of rats consuming theblack tea were significantly less than in controls. Similarly, liver and kidney malondialdehyde concentrationswere significantly lower in the experimental group, while jejunoileal mucosa were not affected. Ten weeksof black tea administration caused significantly higher reduced-glutathione levels in the kidneys ofblack tea-administered rats, and a significant negative correlation was observed between kidney malondialdehydeand glutathione concentrations. Conclusions: These findings provide evidence that long term black teasupplementation is capable of protecting both plasma proteins and plasma lipids from oxidative injury,and demonstrate that chronic black tea administration protects both liver and kidney tissues - but notthe jejunoileal mucosa - against oxidation.

Keywords: Thiobarbituric Acid Reactive Substances - analysis, Tea - chemistry, Reference Standards, Random Allocation, Plant Extracts - pharmacology, Malondialdehyde - blood, Antioxidants - pharmacology, Liver - drug effects, Lipids - blood, Lipid Peroxidation - drug effects, Kidney - drug effects, Glutathione - analysis, Blood Proteins - drug effects, Administration, Oral



01 January 2023 : Editorial  

Editorial: Current Status of Two Adjuvanted Malaria Vaccines and the World Health Organization (WHO) Strategy to Eradicate Malaria by 2030

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939357

Med Sci Monit 2023; 29:e939357


26 January 2023 : Editorial  

Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread

Med Sci Monit In Press; DOI: 10.12659/MSM.939580  

19 January 2023 : Clinical Research  

Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...

Med Sci Monit In Press; DOI: 10.12659/MSM.938892  

27 December 2022 : Clinical Research  

Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...

Med Sci Monit 2022; 28:e938926

In Press

27 Jan 2023 : Database Analysis  

Association Between Neutrophil-Lymphocyte Ratio and All-Cause Mortality in Critically Ill Patients with Chr...

Med Sci Monit In Press; DOI: 10.12659/MSM.938554  

27 Jan 2023 : Clinical Research  

Proposal for a Simple Equation for Limb Muscle Weight Calculation

Med Sci Monit In Press; DOI: 10.12659/MSM.938606  

26 Jan 2023 : Editorial  

Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global Spread

Med Sci Monit In Press; DOI: 10.12659/MSM.939580  

20 Jan 2023 : Clinical Research  

A Study of 42 Partially Edentulous Patients with Single-Crown Restorations and Implants to Compare Bone Los...

Med Sci Monit In Press; DOI: 10.12659/MSM.939225  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750