Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 March 2006

Human seminal plasma nitric oxide: Correlation with sperm morphology and testosterone.

Ivan Huang, Jeff Jones, Omid Khorram

Med Sci Monit 2006; 12(3): CR103-106 :: ID: 447106

Abstract

Background: The purpose of this study was to evaluate levels of NitricOxide (NO) and testosterone (T) in seminal plasma of men with normal and abnormal semen analysis (SA),and determine if correlations between seminal plasma NO, T and sperm quality exists. Material/Methods:Subjects consisted of 9 men with a normal SA and 24 men with abnormality of at least one parameter inthe SA. Seminal plasma NO was analyzed using chemiluminescence, and testosterone by immunoassay. Results:Men with normal and abnormal SA were of comparable age and had no significant medical history. Subjectswith abnormal semen had significant impairment of at least one parameter of their SA. Mean seminal plasmaT levels were significantly lower in subjects with abnormal SA. In subjects with abnormal SA, there wasa significant positive correlation between seminal plasma NO and sperm morphology, as well as a positivetrend between seminal plasma NO and T. In all subjects there was a highly significant positive correlationbetween sperm morphology and seminal plasma T. Conclusions: NO and testosterone are detectable in seminalplasma and are potentially involved in spermatogenesis. Low levels of seminal plasma NO and T are associatedwith defects in sperm morphology.

Keywords: Cell Count, Nitric Oxide - analysis, Radioimmunoassay, Semen - chemistry, Sperm Motility - physiology, Spermatozoa - physiology, Testosterone - analysis

Add Comment 0 Comments

Editorial

01 May 2024 : Editorial  

Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)

Dinah V. Parums

DOI: 10.12659/MSM.944927

Med Sci Monit 2024; 30:e944927

In Press

Clinical Research  

Differential Inflammatory Responses in Adult and Pediatric COVID-19 Patients: Implications for Long-Term Co...

Med Sci Monit In Press; DOI: 10.12659/MSM.944052  

Clinical Research  

Effectiveness of Shoulder Taping in Treating Hemiplegic Shoulder Subluxation: A Randomized Controlled Study...

Med Sci Monit In Press; DOI: 10.12659/MSM.944222  

Clinical Research  

Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Di...

Med Sci Monit In Press; DOI: 10.12659/MSM.944116  

Database Analysis  

ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma

Med Sci Monit In Press; DOI: 10.12659/MSM.943523  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750