Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 March 2006

Clinical and epidemiological features of hospitalized acute Q fever cases fromSplit-Dalmatia County (Croatia), 1985-2002.

Boris Luksić, Volga Punda-Polić, Ivo Ivić, Ivica Bradarić, Nikola Bradarić

Med Sci Monit 2006; 12(3): CR126-131 :: ID: 447111

Abstract

Background: Q fever shows a wide diversity of clinical manifestation. Qfever is endemic in northern Croatia, but the epidemiological and clinical characteristics of this diseasein various ecological areas of southern Croatia are unclear. Material/Methods: From January 1985 to December2002, acute Q fever cases hospitalized at Split University Hospital were analyzed. Acute Q fever wasdefined as fever (>38 degrees C) with clinical findings in lung and/or liver verified by serologic testingwith Coxiella burnetii phase II antigen. Results: During the period of observation, 155 acute Q fevercases were hospitalized. The mean incidence of acute Q fever in the study region was 0.20/100,000/year(95%CI:0-0.78) in the coastal area and 4.64/100,000/year (95%CI:0.44-8.85) in the non-coastal areas,with a male predominance (chi(2)=60.0; p=0.0000) and a mean male to female ratio of 4.2:1. People ofessentially all ages (4-76 years) were affected, the highest rate of infection being recorded in 20-to 49-year-old age groups. In contrast to adults, girls were more frequently affected than boys (2:1).No case of acute Q fever was recorded on any of the nearby islands. Clinically, acute Q fever most commonlypresented with both pneumonia and hepatitis (60.0%), followed by pneumonia (25.8%), hepatitis (9.0%),and nonspecific febrile illnesses (5.2%). Conclusions: C. burnetii is endemic in rural, coastal, andnon-coastal areas of southern Croatia and is associated with stock breeding. In these areas, Q feveroccurs sporadically and epidemically. Males 20-49 years of age were the prevalent cases.

Keywords: Seroepidemiologic Studies, Seasons, Risk Factors, Q Fever - pathology, Prevalence, Pneumonia, Rickettsial - microbiology, Incidence, Age Distribution, Hospitalization, Hepatitis - microbiology, Geography, Fluorescent Antibody Technique, Indirect, Croatia - epidemiology, Coxiella burnetii - immunology, Antibodies, Bacterial - analysis

Add Comment 0 Comments

Editorial

01 May 2024 : Editorial  

Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)

Dinah V. Parums

DOI: 10.12659/MSM.944927

Med Sci Monit 2024; 30:e944927

In Press

07 May 2024 : Clinical Research  

Treatment of AVN-Induced Proximal Pole Scaphoid Nonunion Using a Fifth and Fourth Extensor Compartmental Ar...

Med Sci Monit In Press; DOI: 10.12659/MSM.944553  

16 Mar 2024 : Clinical Research  

Diagnostic Efficiency of ACR-TIRADS Score for Differentiating Benign and Malignant Thyroid Nodules of Vario...

Med Sci Monit In Press; DOI: 10.12659/MSM.943228  

08 May 2024 : Clinical Research  

Effect of Individualized PEEP Guided by Driving Pressure on Diaphragm Function in Patients Undergoing Lapar...

Med Sci Monit In Press; DOI: 10.12659/MSM.944022  

21 Mar 2024 : Clinical Research  

Impact of Serum Vitamin D, B6, and B12 and Cognitive Functions on Quality of Life in Peri- and Postmenopaus...

Med Sci Monit In Press; DOI: 10.12659/MSM.943249  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750