01 March 2006
White blood cell scintigraphy in the diagnosis of infection of endovascular prostheses within the first month after implantation.
Mauro Liberatore, Maria Misuraca, Enrico Calandri, Luigi Rizzo, Francesco Speziale, Anna Paola Iurilli, Cristos AnagnostouMed Sci Monit 2006; 12(3): MT5-9 :: ID: 447116
Abstract
Background: 99mTc-HMPAO-labeled leukocyte scintigraphy (WBCs) is usefulin the diagnosis of vascular graft infection. However, false positives can occur in the early postoperativeperiod. There are no data concerning the usefulness of WBCs in detecting endovascular prosthesis infectionduring this period. The aim of our study was to assess the reliability of WBCs in the diagnosis of earlyinfection after endovascular prosthesis implantation. Material/Methods: 23 patients treated with endovasculargrafts were submitted to preoperative diagnostic screening and to 3 WBCs (1 week before, 1 week after,and 1 month after surgery). After the last WBCs, all patients underwent a 14-month follow-up (range 6-37months, median 12 months). Results: Three patients died, at 3, 4 and 5 months after surgery respectively.At the end of the follow-up, the presence of infection was demonstrated in one patient. Of the 70 WBCsperformed, 4 gave positive results. No positive scintigraphies were obtained in the preoperative period.A positive scintigraphy was found one week after surgery in a patient who showed lymphorrhage at thesite of surgical access. In the same patient, the scintigraphic result returned to normal at 1-monthscintigraphy. At 12-month follow-up the patient did not present signs of infection. Three positive scintigraphieswere obtained in the same patient. In this patient clinical symptoms of graft infection became evidentabout 19 months after surgery. WBCs was repeated and showed extension of the infection. The infectionwas confirmed at surgery. Conclusions: WBCs do not provide false-positives in the first month after endovascularprosthesis implantation.
Keywords: Leukocyte Count, Ultrasonography, Doppler, Color, Tomography, X-Ray Computed, Time Factors, Technetium Tc 99m Exametazime - diagnostic use, Radiopharmaceuticals - diagnostic use, Radiography, Abdominal, Prosthesis-Related Infections - radionuclide imaging, Leukocytes, Infection - diagnosis, Follow-Up Studies, Femoral Artery - surgery, Blood Vessel Prosthesis Implantation - adverse effects, Blood Vessel Prosthesis - adverse effects, Aorta - surgery, Angiography, Aged, 80 and over
Editorial
01 July 2026 : Editorial
Editorial: The WHO Identifies Ebola Disease Due to Bundibugyo Virus as a Public Health Emergency of International Concern (PHEIC) as Vaccine Development AcceleratesDOI: 10.12659/MSM.954627
Med Sci Monit 2026; 32:e954627
In Press
Clinical Research
Comparative Effectiveness of a Nurse-Led Care Model vs Usual Care in Rheumatoid Arthritis: A Longitudinal C...Med Sci Monit In Press; DOI: 10.12659/MSM.953211
Clinical Research
Impact of Treatment Modality on Pain, Sexual Function, and Psychological Well-Being in Patients With Bartho...Med Sci Monit In Press; DOI: 10.12659/MSM.952422
Clinical Research
Association Between Radiographic Knee Osteoarthritis, Pre-Fracture Mobility, and Hip Fracture Patterns in O...Med Sci Monit In Press; DOI: 10.12659/MSM.952678
Clinical Research
Association Between Total Cholesterol–to–High-Density Lipoprotein Ratio and Gestational Hypertension: A Cas...Med Sci Monit In Press; DOI: 10.12659/MSM.952395
Most Viewed Current Articles
17 Jan 2024 : Review article 14,176,084
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
13 Nov 2021 : Clinical Research 3,757,530
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
14 Dec 2022 : Clinical Research 2,466,116
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research 708,768
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387






