Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 January 1998

Serum myoglobin as a marker of skeletal muscle damage from extracorporeal shockwave lithotripsy (ESWL)

Aleksandra Kochańska-Dziurowicz, Andrzej Prajsner, Wojciech Szewczyk, Marzena Jaworska-Kik

Med Sci Monit 1998; 4(6): CR951-954 :: ID: 451730

Abstract

Extracorporeal shock wave lithotripsy (ESWL) is an effective method to treat kidney stones. The soft tissues surrounding the kidney may be damaged as the shock wave passes through on its way to the stone. We measured serum myoglobin concentration to assess skeletal muscle damage as a side effect of ESWL in patients treated for stones in a solitary kidney using shock waves generated at 19 kV with two different total impulse counts - 4000 or 2000 -applied in one session. Sixty-six patients, aged 35-65, were studied. Twenty four patients were excluded with signs of urinary tract infections. Patients were randomly assigned to either 2000 or 4000 impulse count treatment groups. Serum myoglobin concentration was measured by RIA. In the 4000 impulse treatment group, mean serum myoglobin was 75.2±29.8 ng/ml before ESWL, was 82.2±33.7 ng/ml(9.3% increase from baseline) on day 1 after ESWL, and was 93.0±44.9 ng/ml (23.7% increase from baseline) on day 3 after ESWL. In the 2000 impulse treatment group, mean serum myoglobin was 86.6±27.2 ng/ml before ESWL, was 96.2±41.2 ng/ml (11.1% increase from baseline) on day 1 after ESWL, and was 78.9±36.9 ng/ml (8.9% decrease from baseline) on day 3 after ESWL. Changes within and between treatment groups were not statistically significant (p>0.05). These small increases in serum myoglobin concentration after ESWL may indicate skeletal muscle damage. Greater and more persistent increases in serum myoglobin seen after a greater number of impulses applied may indicate more muscle damage. Normalization of serum myoglobin concentration indicates that this damage is transient and ESWL produced no evidence of permanent skeletal muscle damage at the doses used. Moreover, we found no statistical difference in serum myoglobin concentration within groups or between groups.

Keywords: kidney stones, treatment, extracorporeal shock wave lithotripsy (ESWL), complications

Add Comment 0 Comments

Editorial

01 June 2024 : Editorial  

Editorial: Concerns as Highly Pathogenic Avian Influenza (HPAI) Virus of the H5N1 Subtype is Identified in Dairy Cows and Other Mammals

Dinah V. Parums

DOI: 10.12659/MSM.945315

Med Sci Monit 2024; 30:e945315

0:00

In Press

Clinical Research  

Comparative Evaluation of Digital Cephalometric Tracing Applications on Mobile Devices and Manual Tracing

Med Sci Monit In Press; DOI: 10.12659/MSM.944628  

0:00

Clinical Research  

Impact of COVID-19-Induced Academic Stress on Insomnia and Suicidal Ideation among Taiwanese Health Trainee...

Med Sci Monit In Press; DOI: 10.12659/MSM.944932  

Review article  

Impact of Workplace Bullying on Nursing Care Quality: A Comprehensive Review

Med Sci Monit In Press; DOI: 10.12659/MSM.944815  

Clinical Research  

Anterior Plate-Supported Cannulated Screw Surgery for Ankle Arthrodesis: Clinical and Radiologic Results in...

Med Sci Monit In Press; DOI: 10.12659/MSM.944452  

Most Viewed Current Articles

17 Jan 2024 : Review article   1,882,405

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research   1,538,203

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research   690,402

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Jan 2022 : Editorial   50,329

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750