Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

17 March 2003

Most ventricular depolarization and repolarization abnormalities are not predictors of arrhythmic events in postinfarction patients with normal intraventricular conduction.

Jan Ruta, Paweł Ptaszyński, Krzysztof Jerzy Wranicz, Halina Bolińska

Med Sci Monit 2003; 9(3): CR131-136 :: ID: 4728


BACKGROUND: Survivors of acute myocardial infarction (AMI) are at increased risk for arrhythmic events (AE), which include sudden death (SD) or sustained ventricular tachycardia (sVT). In the prethrombolytic era, abnormal parameters of depolarization and repolarization were considered to be markers of susceptibility to these events. The purpose of the present study was to assess whether these variables should still be considered predictors of AE in postinfarction patients with normal intraventricular conduction. MATERIAL/METHODS: The study population consisted of 236 survivors of AMI, in whom the parameters of depolarization on SAECG (QRSd, LAS, RMS, LPs) and repolarization on ECG (QTc-max, QTd) were assessed before hospital discharge. The patients were followed for 18 months, and all episodes of SD and sVT were recorded. RESULTS: During long-term observation, 3 patients died from SD, and sVT occurred in 1 patient. Univariate Cox regression analysis showed that among the SA-ECG and ECG variables, only QRSd was significantly related to the incidence of AE (p<0.04). A comparison of event-free survival curves by the Kaplan-Meier method at the dichotomy limit of 119ms showed significantly worse prognosis in patients with QRSd>119ms (p<0.01). CONCLUSIONS: In postinfarction patients with normal intraventricular conduction treated in the acute and chronic phase of MI according to recent management strategies, QRSd>119ms on SAECG is associated with arrhythmic events. Other parameters of depolarization, such as LAS, RMS, and positive LPs, and also repolarization, such as prolonged QTc-max and QTd, seem to be of little use in predicting these events.

Keywords: Heart Conduction System - physiopathology, Myocardial Infarction - complications, Tachycardia, Ventricular - etiology, Tachycardia, Ventricular - physiopathology

Add Comment 0 Comments

641 1


01 May 2023 : Editorial  

Editorial: Twenty Years On from Sequencing the Human Genome, Personalized/Precision Oncology Prepares to Meet the Challenges of Checkpoint Inhibitor Therapy

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.940911

Med Sci Monit 2023; 29:e940911


In Press

31 May 2023 : Review article  

Prevalence, Diagnosis, and Management of Eclampsia and the Need for Improved Maternal Care: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.939919  

30 May 2023 : Clinical Research  

A Case-Control Study of Cognitive Function in Patients with End-Stage Renal Disease Before and After Hemodi...

Med Sci Monit In Press; DOI: 10.12659/MSM.940409  

30 May 2023 : Review article  

A Review of the Role of the Zebrafish (Danio reiro) in Preclinical and Clinical Models of Biomarker Identif...

Med Sci Monit In Press; DOI: 10.12659/MSM.940550  

30 May 2023 : Database Analysis  

The COVID-19 Crisis and the Incidence of Alcohol-Related Deaths in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.940904  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750