Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

28 January 2003

Helicobacter pylori aeropositivity and the incidence of hyperemesis gravidarum.

Arezo Salimi-Khayati, Hajar Sharami, Fariborz Mansour-Ghanaei, Saideh Sadri, Mohammad-Sadegh Fallah

Med Sci Monit 2003; 9(1): CR12-15 :: ID: 4778


BACKGROUND: We studied the incidence of Helicobacter pylori infection in patients with hyperemesis gravidarum (HG) in comparison with non-HG pregnant women, and investigated whether there was a correlation between positive serology for H. pylori IgG, the time of onset, and the duration of HG symptoms. MATERIAL/METHODS: 54 pregnant women with HG were enrolled in a matched case - control study. For each case in the group, a pregnant woman without HG matched for age, parity and gestational age was selected as a control. The patients in the experimental group were asked the exact time of symptom onset, and both groups were monitored during pregnancy for symptoms and outcome. Serum H. pylori IgG antibody was measured by enzyme-linked immunosorbent assay (ELISA). RESULTS: Positive serum H. pylori IgG antibody was detected in 88.9% of the patients in the experimental group vs. 40.7% of the controls (P<0.001). Three of the four patients with abortions in each group were seropositive. Age, parity, level of education, symptom onset, and duration and outcome of pregnancy were comparable in both seropositive and seronegative patients with HG. CONCLUSIONS: Although more patients with HG were seropositive for H. pylori infection than controls, we were not able to demonstrate correlation between seropositivity for H. pylori and the time of onset or duration of HG symptoms. Although H. pylori infection may be an important factor in exacerbating HG, it may not represent the sole cause of the disease.

Keywords: Helicobacter Infections - blood, Hyperemesis Gravidarum - microbiology

Add Comment 0 Comments

537 5


01 June 2023 : Editorial  

Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic Preparedness

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.941209

Med Sci Monit 2023; 29:e941209


In Press

08 Jun 2023 : Clinical Research  

Risk Factors for New Vertebral Compression Fracture After Percutaneous Vertebral Augmentation: A Retrospect...

Med Sci Monit In Press; DOI: 10.12659/MSM.940134  

08 Jun 2023 : Clinical Research  

A Nomogram for Identifying HR+/Her2- Breast Cancer Patients with Positive Sentinel Lymph Nodes and Omitted ...

Med Sci Monit In Press; DOI: 10.12659/MSM.940124  

08 Jun 2023 : Clinical Research  

Burden of COVID-19 on Mental Health of Resident Doctors in Poland

Med Sci Monit In Press; DOI: 10.12659/MSM.940208  

08 Jun 2023 : Clinical Research  

Risk Prediction for Rapidly Progressive Interstitial Lung Disease in Anti-MDA5-Positive Dermatomyositis: Th...

Med Sci Monit In Press; DOI: 10.12659/MSM.940251  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750