Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 July 1996

Spiral waves in a 2-D model of fibrillating heart and a new way to break them

Paweł Strumiłło, Thomas S. Durrani

Med Sci Monit 1996; 2(4): MT495-504 :: ID: 500002

Abstract

Spatio-temporal patterns generated in a bi-layered two dimensional array of interconnected nonlinear elements are studied in relation with modelling of the heart ventricular electrodynamic instability. The rectangular lattice of nonlinear elements is mapped onto cylindrical surface to approximate the geometry of the heart ventricles. A novel explanation for the mechanism of heart fibrillation (attributed to multiple spiral waves [1,2]) is proposed based on the concept that depolarised and refractory cells of the heart tissue act as two spatially distributed competing populations (analogous to the predator-prey situation in the dynamic models of interacting species). This novel interpretation of the fibrillation dynamics provides a direct relationship between the complex, spatio-temporal spiral patterns of tissue activation and the periodic body surface electrocardiographic signal recorded during this heart arrhythmic condition. These findings lead to the proposal for a new, low energy, multi-pulse stimulation technique for termination of the deadly spiral "autowave attractor".

Keywords: Heart, Ventricular Fibrillation, Computer Simulation

Add Comment 0 Comments

Editorial

01 November 2024 : Editorial  

Editorial: Artificial Intelligence (AI), Digital Image Analysis, and the Future of Cancer Diagnosis and Prognosis

Dinah V. Parums

DOI: 10.12659/MSM.947038

Med Sci Monit 2024; 30:e947038

0:00

In Press

Clinical Research  

Adipose-Derived Mesenchymal Stem Cells from Arthritis Patients: Differential Modulation of CD4⁺ T Cell Acti...

Med Sci Monit In Press; DOI: 10.12659/MSM.945273  

0:00

Review article  

Surgical Advances in the Treatment of Acromioclavicular Joint Injury: A Comprehensive Review

Med Sci Monit In Press; DOI: 10.12659/MSM.942969  

0:00

Clinical Research  

Analysis of Mortality Causes and Locations in Veterans with ALS: A Decade Review

Med Sci Monit In Press; DOI: 10.12659/MSM.945816  

0:00

Clinical Research  

Impact of Prior Cesarean Delivery on Pregnancy Outcomes and Hemorrhage Risks in Complete Placenta Previa: A...

Med Sci Monit In Press; DOI: 10.12659/MSM.944432  

0:00

Most Viewed Current Articles

17 Jan 2024 : Review article   6,511,914

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research   1,913,219

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

16 May 2023 : Clinical Research   695,669

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

07 Jan 2022 : Meta-Analysis   261,779

Efficacy and Safety of Light Therapy as a Home Treatment for Motor and Non-Motor Symptoms of Parkinson Dise...

DOI :10.12659/MSM.935074

Med Sci Monit 2022; 28:e935074

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750