Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 November 1996

Comparative study of enzyme activity in lung tissue of patients with squamous cell lung cancer

Andrzej Dżugaj, Jerzy Kołodziej, Daria Dziewulska-Szwajkowska, Bożena Jungowska-Klin, Zofia Kozubek, Małgorzata Łozińska-Gabska, Antonina Poloczek-Adamowicz, Maria Przybylska-Wojtyszyn, Krzysztof Skałecki, Andrzej Staniszewski

Med Sci Monit 1996; 2(6): CR716-719 :: ID: 500121


The activities and some properties of acid and alkaline phosphatases, inorganic pyrophosphatase, 5'-nucleotidase, fructose-1,6-bisphosphatase and aminotransferases in homogenates of normal and cancer lung tissue were investigated. The study group consisted of 26 patients treated in the Department of Thoracic Surgery, Wrocław Medical University, Wrocław. All patients were men, aged 49 to 69 years (mean, 58 years), with a histologically proven diagnosis of squamous cell carcinoma, stage I - 17 patients (65.4%), stage II - 3 patients (11.6%), stage IIIa - 5 patients (19.2%) and stage IIIb - one patient (3.8%). All patients underwent pulmonary resection including pneumonectomy in 12 cases (46.2%), lobectomy in 11 cases (42.3%) and limited surgery (i.e. wedge resection) in 3 cases (11.55%). Samples for determining enzymatic activity were obtained from postoperative specimens. Preliminary results indicate that activities of inorganic pyrophosphatase in lung cancer tissue are markedly elevated. The index of proteolytic modification of fructose-1,6-bisphosphatase is also increased.

Keywords: tumour marker, squamous cell lung cancer, Lung, fructose-1,6-bisphosphatase, Inorganic Pyrophosphatase



04 June 2022 : Editorial  

Editorial: Acute Hepatitis of Unknown Origin in Children. Is Autoimmunity at Play?

Nahum Mendez-Sanchez, Shreya C. Pal
Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

DOI: 10.12659/MSM.937371

Med Sci Monit 2022; 28:e937371

In Press

23 Jun 2022 : Clinical Research  

A Real-World Study to Compare the Safety and Efficacy of Paritaprevir/Ombitasvir/Ritonavir and Dasabuvir, w...

Med Sci Monit In Press; DOI: 10.12659/MSM.936706  

22 Jun 2022 : Clinical Research  

A Single-Center Study Comparing the Effects of Thoracic Spine Manipulation vs Mobility Exercises in 26 Offi...

Med Sci Monit In Press; DOI: 10.12659/MSM.937316  

21 Jun 2022 : Clinical Research  

Optimal Timing and Outcomes of Minimally Invasive Approach in Acute Biliary Pancreatitis

Med Sci Monit In Press; DOI: 10.12659/MSM.937016  

16 Jun 2022 : Clinical Research  

Renal Manifestations in Inflammatory Bowel Disease: A Cohort Study During the Biologic Era

Med Sci Monit In Press; DOI: 10.12659/MSM.936497  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750