03 March 1997
Fine-structure of the transition from the sclera to the corneoscleral trabeculum in open-angle glaucoma
Piroska Follmann, Ildikó Süveges, László ValuMed Sci Monit 1997; 3(2): BR139-143 :: ID: 500624
Abstract
Background:The fine structure of the connective tissue constituents of the transition from the sclera to the corneoscleral trabeculum was studied with transmission electron microscopy in open-angle glaucoma.
Material/Methods: 29 cases were investigated. The age of the patients ranged between 50 and 85 years, the glaucoma has lasted from 2 to 30 years. The specimens were taken during trabeculectomy after previous local drug treatment and/or laser and surgical interventions. The normal material derived from eyes enucleated because of intraocular tumours, without intraocular pressure elevation.The specimens were investigated with transmission electron microscopy.
Results: The irregular scleral fibre system gradually arranged into bundles. The bundles were getting finer and finer, and next mixed with the tissue elements of the cornea, chiefly with those of Descemet's membrane. Then the characteristic fourlayered structure of the trabecular bundles developed. These considerable tissue changes were obviously the morphologic basis of the peculiar function of the trabecular meshwork. In the sclera essential pathologic changes could not be demonstrated during the progression of the disease. In the transitional area, however, according to the change of the tissue structure, the quantity of the pathologic alterations gradually increased. In the fully developed trabecular bundles all the pathologic alterations already known in open-angle glaucoma could be detected. This tendency to develop alterations, however, could be recognized in other types of glaucoma, too.
Conclusions: The data on the alterations in the transitional zone from the sclera to the corneoscleral trabeculum may add further information on the sequence of the development of alterations of the morphologic changes found in open-angle glaucoma. These may be similar in morphologic features to those found as age-related changes.
Keywords: Sclera, corneoscleral trabeculum, fine structure of transition, open-angle glaucoma, transmission electron microscopy
Editorial
01 February 2023 : Editorial
Editorial: The XBB.1.5 (‘Kraken’) Subvariant of Omicron SARS-CoV-2 and its Rapid Global SpreadDOI: 10.12659/MSM.939580
Med Sci Monit 2023; 29:e939580
SARS-CoV-2/COVID-19
19 January 2023 : Clinical Research
Evaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...Med Sci Monit In Press; DOI: 10.12659/MSM.938892
19 January 2023 : Clinical Research
Determining the Impact of the COVID-19 Pandemic on Dental Care in the Serbian Adult Population: An Online Q...Med Sci Monit 2023; 29:e939238
27 December 2022 : Clinical Research
Effect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...Med Sci Monit 2022; 28:e938926
10 December 2022 : Clinical Research
Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...Med Sci Monit 2022; 28:e938647
In Press
01 Feb 2023 : Clinical Research
Comparison of 3 Enzyme-Linked Immunoassay Methods to Evaluate Serum Concentrations of Infliximab and Antibo...Med Sci Monit In Press; DOI: 10.12659/MSM.939084
31 Jan 2023 : Clinical Research
Balloon Dilation Eustachian Tuboplasty Combined with Tympanotomy Tube Insertion for Treatment of Refractory...Med Sci Monit In Press; DOI: 10.12659/MSM.938879
31 Jan 2023 : Clinical Research
Comparison of Vision Correction and Corneal Thickness at 180-Day Follow-Up After Femtosecond Laser-Assisted...Med Sci Monit In Press; DOI: 10.12659/MSM.939099
30 Jan 2023 : Clinical Research
Splenic Artery Steal Syndrome in Patients with Liver Cirrhosis: A Retrospective Clinical StudyMed Sci Monit In Press; DOI: 10.12659/MSM.938998
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952