Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 July 1997

Colorectal carcinoma in patients under 40 years of age: clinical presentation and early effects of treatment

Krzysztof Bielecki, Piotr Kamiński, Mirosław Klukowski, Andrzej W Włodarczyk

Med Sci Monit 1997; 3(4): CR499-503 :: ID: 501343


During the years 1988 to 1995, 327 patients were treated for primary colorectal carcinoma; 15 (5.4%) of them (11 women, 4 men) were 26-40 years old, with a mean age of 30.8 years. The majority of tumors, 11 (73.3%) were found in the left colon. This group was retrospectively compared with the remaining 312 patients in order to find out whether there were any differences in clinical presentation and early effects of the treatment. Carcinoma of the transverse colon was more frequent in young adults (20%) than in patients over 40 years of age (5.7%). This difference was statistically significant. In one patient carcinoma occurred secondary to ulcerative colitis of a 10-year duration. In the remaining patients the time from the onset of symptoms and diagnosis of the disease to surgical treatment ranged from 2 weeks to 18 months (mean time=6.5 months). All patients received surgical treatment. Two (2) women were operated urgently because of an ileus. Fourteen (14) patients underwent resection procedures, most frequently anterior rectal amputation. Intestinal anastomosis was not performed in 3 adults. Ten (10) patients received surgical procedure as a definitive treatment. Postoperative complications occurred in 5 (33.3%) adults. None of the patients died. Most patients (60%) had carcinoma of C and D stages of progression according to the modified Dukes classification; there was a similar incidence of advanced carcinoma in older patients (56.4%). Poorly differentiated adenocarcinoma (33.3%) and mucinous carcinoma (20%) were more frequent in younger than older patients (16.9% and 5.4%, respectively). The difference in the occurrence of mucinous carcinoma was statistically significant. On the basis of our data, we may conclude that there are no significant differences in the clinical picture and natural history of colorectal carcinoma in patients of these two groups apart from a more frequent occurrence of mucinous carcinoma in young patients.

Keywords: large intestine, mucinous carcinoma, carcinoma in young patients

Add Comment 0 Comments


01 April 2024 : Editorial  

Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug Resistance

Dinah V. Parums

DOI: 10.12659/MSM.944600

Med Sci Monit 2024; 30:e944600


In Press

10 Apr 2024 : Clinical Research  

Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...

Med Sci Monit In Press; DOI: 10.12659/MSM.942612  

06 Mar 2024 : Clinical Research  

Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...

Med Sci Monit In Press; DOI: 10.12659/MSM.941102  

06 Mar 2024 : Clinical Research  

Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943884  

08 Mar 2024 : Clinical Research  

Evaluation of Foot Structure in Preschool Children Based on Body Mass

Med Sci Monit In Press; DOI: 10.12659/MSM.943765  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750