Many research projects exploring nature of low-frequency (LF) electromagnetic field (EMF) interactions with living matter have been established in the last two decades. In our study we focused on electromacnetic fields generated by power lines and microwave frequencies. The results, although still inconclusive, in some cases show strong correlation between parameters of experimentally generated EMF and observed bioeffects. Parallelly several authors have demonstrated that living systems may emit low-intensity radiation of high coherence covering broad spectrum of frequencies. Results emerged new theories related to hypothetical system of electromagnetic bioinformation which might be influenced by conventional or unconventional electro- and magnetotherapy. In the part I of our paper we demonstrated that application of bioelectronic wave modulator (BICOM) in case of a rat tumor Ñ Morris hepatoma - may affect the tumour growth and metastatic ability. Now we report about similar effects observed during the next series of experiments. A comparable device VEGA SELECT 709 was applied using both in vitro and in vivo conditions and pre-selected parameters. In experimental groups average tumour growth rate was higher (in vitro exposition: 1.73±0.18 g/d vs. 1.45±0.12 g/d in control group, p=0.006; in vivo exposition: 1.77±0.2 g/d (group A) vs. 1.46±0.24 g/d in control group, p=0.01) whereas average survival time was respectively reduced. These results suggest possibility of a resonance response from the tumour tissue. It seems that LF EMF stimulation may not be indicated as a therapeutic approach in case of advanced tumours.

Keywords: low-frequency electromagnetic field, bioradiation, resonance, proliferation, Morris hepatoma, electro- and magnetotherapy