Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

Heart rate variability: monitoring of the autonomic nervous systems activity during general anesthesia

Wojciech Płazak, Tomasz Muszyński, Alicja Macheta, Henryk Podziorny, Jacek Łach, Piotr Podolec, Maria Olszowska, Krystyna Potocka-Płazak, Janusz Andres

Med Sci Monit 1999; 5(5): CR925-928 :: ID: 503415


Background: Heart rate variability (HRV) monitoring is a new, non-invasive method in the assessment of the autonomic nervous systems activity. LF/TP is the index of adrenergic activation, HF/TP is the index of cholinergic activation and the LF/HF ratio represents the dynamic balance between both parts of the autonomic system. The aim of this study was to evaluate the advantage of intraoperative HRV (spectral analysis) as a method of autonomic nervous system activity assessment, in comparison with traditional variables such as heart rate and blood pressure. Methods: 21 ASA I patients, aged between 17 and 72 years (mean age - 40.5), following surgery on the facial cranium due to neoplasmic changes were anesthetized by means of thiopental and suxamethonium for induction and nitrous oxide with fentanyl for anesthesia maintenance. HRV indices were calculated from 5-minute fragments of the recorded ECG. Results: LF/TP decreased following intubation and during anesthesia maintenance (p < 0.001). HF/TP decreased during anesthesia induction and intubation (p < 0.05), following intubation (p < 0.001) and during anesthesia maintenance (p < 0.05) and increased during and following extubation (p < 0.05). The LF/HF ratio decreased during the first 5 minutes following extubation (p < 0.05). The heart rate was elevated following intubation (p < 0.05) and had its lowest value following extubation (p < 0.01). The blood pressure remained unchanged during the procedure. Conclusion: HRV monitoring might provide a more convenient index of autonomic activity during general anesthesia, than classical estimates based on the heart rate or blood pressure.

Keywords: general anesthesia, Holter monitoring, Electrocardiography, Autonomic Nervous System, cholinergic, adrenergic

Add Comment 0 Comments

655 4


01 November 2023 : Editorial  

Editorial: Factors Driving New Variants of SARS-CoV-2, Immune Escape, and Resistance to Antiviral Treatments as the End of the COVID-19 Pandemic is Declared

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville,

DOI: 10.12659/MSM.942960

Med Sci Monit 2023; 29:e942960


In Press

29 Nov 2023 : Laboratory Research  

CTRP13 Mitigates Endothelial Cell Ferroptosis via the AMPK/KLF4 Pathway: Implications for Atherosclerosis P...

Med Sci Monit In Press; DOI: 10.12659/MSM.942733  

28 Nov 2023 : Clinical Research  

Impact of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography on Therapeutic Decisions and ...

Med Sci Monit In Press; DOI: 10.12659/MSM.942122  

28 Nov 2023 : Clinical Research  

Long-Term Outcomes of Decompression and Grafting in Acute Pathological Proximal Femur Fractures in Children...

Med Sci Monit In Press; DOI: 10.12659/MSM.943031  

27 Nov 2023 : Clinical Research  

Comparison of Outcomes from Emergency Admissions to a Major Trauma Center in Turkey of 1646 Elderly Patient...

Med Sci Monit In Press; DOI: 10.12659/MSM.942916  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750