Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

Heart rate variability: monitoring of the autonomic nervous systems activity during general anesthesia

Wojciech Płazak, Tomasz Muszyński, Alicja Macheta, Henryk Podziorny, Jacek Łach, Piotr Podolec, Maria Olszowska, Krystyna Potocka-Płazak, Janusz Andres

Med Sci Monit 1999; 5(5): CR925-928 :: ID: 503415


Background: Heart rate variability (HRV) monitoring is a new, non-invasive method in the assessment of the autonomic nervous systems activity. LF/TP is the index of adrenergic activation, HF/TP is the index of cholinergic activation and the LF/HF ratio represents the dynamic balance between both parts of the autonomic system. The aim of this study was to evaluate the advantage of intraoperative HRV (spectral analysis) as a method of autonomic nervous system activity assessment, in comparison with traditional variables such as heart rate and blood pressure. Methods: 21 ASA I patients, aged between 17 and 72 years (mean age - 40.5), following surgery on the facial cranium due to neoplasmic changes were anesthetized by means of thiopental and suxamethonium for induction and nitrous oxide with fentanyl for anesthesia maintenance. HRV indices were calculated from 5-minute fragments of the recorded ECG. Results: LF/TP decreased following intubation and during anesthesia maintenance (p < 0.001). HF/TP decreased during anesthesia induction and intubation (p < 0.05), following intubation (p < 0.001) and during anesthesia maintenance (p < 0.05) and increased during and following extubation (p < 0.05). The LF/HF ratio decreased during the first 5 minutes following extubation (p < 0.05). The heart rate was elevated following intubation (p < 0.05) and had its lowest value following extubation (p < 0.01). The blood pressure remained unchanged during the procedure. Conclusion: HRV monitoring might provide a more convenient index of autonomic activity during general anesthesia, than classical estimates based on the heart rate or blood pressure.

Keywords: general anesthesia, Holter monitoring, Electrocardiography, Autonomic Nervous System, cholinergic, adrenergic



04 June 2022 : Editorial  

Editorial: Acute Hepatitis of Unknown Origin in Children. Is Autoimmunity at Play?

Nahum Mendez-Sanchez, Shreya C. Pal
Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

DOI: 10.12659/MSM.937371

Med Sci Monit 2022; 28:e937371


27 June 2022 : Clinical Research  

Shoulder Injury Related to Vaccine Administration (SIRVA) in 16 Patients Following COVID-19 Vaccination Who...

Med Sci Monit In Press; DOI: 10.12659/MSM.937430  

27 May 2022 : Clinical Research  

Factors Associated with Falls During Hospitalization for Coronavirus Disease 2019 (COVID-19)

Med Sci Monit 2022; 28:e936547

In Press

30 Jun 2022 : Clinical Research  

Antioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty

Med Sci Monit In Press; DOI: 10.12659/MSM.936335  

28 Jun 2022 : Meta-Analysis  

Urodynamics in Early Diagnosis of Diabetic Bladder Dysfunction in Women: A Systematic Review and Meta-Analysis

Med Sci Monit In Press; DOI: 10.12659/MSM.937166  

28 Jun 2022 : Clinical Research  

Serum Calprotectin – a NET Product – as a Biomarker of Disease Activity in Patients with Systemic Lupus Ery...

Med Sci Monit In Press; DOI: 10.12659/MSM.936534  

28 Jun 2022 : Database Analysis  

LINC00963 May Be Associated with a Poor Prognosis in Patients with Cervical Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.935070  

Most Viewed Current Articles

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750