Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

Humoral and cellular immunity rates in chemical plant workers producing dust pesticides

Piotr Kłuciński, Stefan Kossmann, Jerzy Tustanowski, Daniela Friedek, Bożena Kamińska-Kołodziej

Med Sci Monit 2001; 7(6): CR1270-1274 :: ID: 508175


Background: Exposure to pesticides may affect humoral and cell-mediated immunity. Material and methods: The study group was composed of 24 men employed in the production of dust pesticides and 23 females performing ancillary jobs under conditions of lower pesticide exposure. Chronic bronchitis was diagnosed in 10 males (41.7%) and 13 females (56.5%). The workers were exposed to: triazines, carbamates and dithiocarbamates, carbendazim, captan, dodine, dichlorophenoxy acetic acid (2,4-D), and cupric oxychloride. Silica, kaolin, chalk, and talc were used as carriers. The average workplace air concentrations of pesticides did not exceed the MAC. The serum concentrations of immunoglobulins G, A and M, complement component C3, and circulating immune complexes (CIC) were estimated. The peripheral blood leukocyte count and percentage of CD3, CD4, CD8, CD19 lymphocytes were evaluated.
Results: IgA and CIC concentrations in the female group were higher as compared to controls, whereas the percentage of CD3, CD4, CD8 cells was significantly lower, as opposed to an increased percentage of CD19 cells. The male group showed lower CIC concentrations, and the C3 complement component level was significantly higher. The decreased percentage of CD3 cells was accompanied by a higher CD19 cells ratio. The white blood cell count was higher in the males. No significant changes were found in other immunity parameters.
Conclusion: The results of the study showed changes in some components of humoral and cellular immunity, which may influence damage to the respiratory system.

Keywords: dust pesticides, humoral immunity, cellular immunity

Add Comment 0 Comments

589 6


01 December 2023 : Editorial  

Editorial: Outbreaks of Post-Pandemic Childhood Pneumonia and the Re-Emergence of Endemic Respiratory Infections

Dinah V. Parums

DOI: 10.12659/MSM.943312

Med Sci Monit 2023; 29:e943312


In Press

04 Dec 2023 : Animal Research  

Effects of Intrathecal Ketamine on Cerebrospinal Fluid Levels of Brain-Derived Neurotrophic Factor and Mech...

Med Sci Monit In Press; DOI:  

01 Dec 2023 : Clinical Research  

Risk Factors and Clinical Outcomes of COVID-19 Infection in Multiple Sclerosis Patients: A Retrospective St...

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Review article  

Decoding the Neurological Sequelae of General Anesthesia: A Review

Med Sci Monit In Press; DOI:  

30 Nov 2023 : Clinical Research  

Enhanced Pain Relief and Muscle Growth in Individuals with Low Back Instability: The Impact of Blood Flow R...

Med Sci Monit In Press; DOI:  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379


14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750