Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

Accuracy of beat-to-beat cardiac output monitoring by pulse contour analysis in hemodynamical unstable patients

Oliver Gödje, Reinhard Friedl, Andreas Hannekum

Med Sci Monit 2001; 7(6): MT1344-1350 :: ID: 508432


Background: Continuous determination of cardiac output (CO) by transpulmonary thermodilution calibrated pulse-contour analysis is gaining clinicical acceptance. However there is doubt, whether this method is reliable in hemodynamic instable patients. We compared pulse-contour analysis to thermodilution in patients with profound changes of CO.
Material and methods: 24 patients were investigated. CO was measured by thransthoracic thermodilution and pulse-contour analysis in intervals of 60 min during study periods of 8–44 h without recalibration of the pulse-contour computer. Results of 517 measurements were compared by regression, structural regression and Bland-Altman analyses.
Results: Mean change of CO was 40±27% (range 20–139%), range of systemic vascular resistance was 450 dyn·s/cm–5 – 2360 dyn·s/cm–5. Correlation of pulse-contour analysis CO to thermodilution CO was r=0.88 with p=0.0001, bias was 0.2 l/min with 1.2 l/min standard deviation. Mean CO by pulse-contour analysis did not differ significantly from CO by thermodilution during the study period. There were no influences of heart rate or arterial pressure on the difference between both methods.
Conclusion: CO measurement by arterial pulse-contour analysis is reliable even in patients with profound changes of CO or during hemodynamic instability.

Keywords: Cardiac Output, pulse-contour analysis, Thermodilution, Intensive Care

Add Comment 0 Comments


01 July 2024 : Editorial  

Editorial: The Global Threats of Increasing Antimicrobial Resistance Require New Approaches to Drug Development, Including Molecular Antimicrobial Adjuvants

Dinah V. Parums

DOI: 10.12659/MSM.945583

Med Sci Monit 2024; 30:e945583


In Press

Database Analysis  

Enhanced Outcomes in Femoral Subtrochanteric Fractures Using Long INTERTAN Nails with Titanium Cable Cercla...

Med Sci Monit In Press; DOI: 10.12659/MSM.944383  


Database Analysis  

Trends in HIV/AIDS-Related Mortality and the Impact of Antiretroviral Treatment Strategies in Lu'an City: A...

Med Sci Monit In Press; DOI: 10.12659/MSM.944727  

Review article  

Optimizing Quality of Life in Kidney Transplant Recipients Through Structured Exercise: A Systematic Review...

Med Sci Monit In Press; DOI: 10.12659/MSM.943617  

Clinical Research  

Ultrasound-Guided PRP and SVF Therapy Shows Sustained Improvement in Severe Knee Osteoarthritis: A 12-Month...

Med Sci Monit In Press; DOI: 10.12659/MSM.943975  

Most Viewed Current Articles

17 Jan 2024 : Review article   4,290,652

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799


14 Dec 2022 : Clinical Research   1,595,389

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990


16 May 2023 : Clinical Research   691,055

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387


01 Jan 2022 : Editorial   50,864

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952


Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750