Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

29 January 2009

Influence of long-term exercise training on submaximal and peak aerobic capacity and locomotor economy in adult males with Down's syndrome

Goncalo VIlhena MendoncaABCDEFG, Fernando Duarte PereiraABCDEFG

Med Sci Monit 2009; 15(2): CR33-39 :: ID: 869543


The effect of exercise training on submaximal aerobic capacity and locomotor economy (LE) of Down's syndrome (DS) individuals has never been analyzed and their peak physiological adaptability to long-term physical conditioning is poorly understood. Thus the purpose of the present study was to determine whether DS males could improve their submaximal and peak aerobic capacity and LE after a 28-week training program.
Material and Method
Twelve Caucasian DS males aged 34.5+/-7.0 years (range: 21-49) underwent a 28-week aerobic exercise intervention consisting of two 40-min sessions of ergometer conditioning per week. Body composition was assessed by anthropometric and bioelectrical impedance spectroscopic measurements. Pre- and post-training submaximal physiological response was determined by means of a 2.5-km/h treadmill flat-walk. Graded maximal exercise tests were performed to investigate the participants' peak exercise capacity. Multivariate analyses of variance were performed to explore the influence of training on the subjects' body composition and submaximal and peak aerobic capacity not.
After training, the participants decreased their fat mass from 27.3+/-11.2 to 23.5+/-11.1% (p<0.01) and increased their absolute fat-free mass from 48.4+/-8.6 to 50.8+/-9.3 kg (p<0.01). There were no differences between pre- and post-training locomotor economy (LE). However, the subjects decreased their respiratory exchange ratio from 0.91+/-0.11 to 0.83+/-0.05 (p<0.05) while exercising at the same submaximal workload. Peak exercise capacity improved 27.8% following training (p<0.01).
Despite improving body composition and peak cardiovascular fitness and lipidic oxidation during submaximal exercise, DS males were unable to modify their LE after 28 weeks of exercise intervention.

Keywords: Time Factors, Rest - physiology, Physical Fitness - physiology, Locomotion - physiology, Exercise - physiology, Pulmonary Ventilation - physiology, Down Syndrome - physiopathology, Body Composition - physiology

Add Comment 0 Comments

799 34


01 June 2023 : Editorial  

Editorial: Infectious Disease Surveillance Using Artificial Intelligence (AI) and its Role in Epidemic and Pandemic Preparedness

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.941209

Med Sci Monit 2023; 29:e941209

In Press

01 Jun 2023 : Clinical Research  

Root Canal Numbers and Configurations in 1080 Permanent Canine Teeth in 270 Saudi Subjects Using Cone-Beam ...

Med Sci Monit In Press; DOI: 10.12659/MSM.940472  

01 Jun 2023 : Clinical Research  

Internal Orifice Alloy Closure: A New Procedure for Treatment of Perianal Fistulizing Crohn’s Disease

Med Sci Monit In Press; DOI: 10.12659/MSM.940873  

01 Jun 2023 : Clinical Research  

Effectiveness of Needle Aspiration versus Surgical Excision for Symptomatic Synovial Cysts of the Hip: A Si...

Med Sci Monit In Press; DOI: 10.12659/MSM.940187  

01 Jun 2023 : Clinical Research  

Influence of Insulin Resistance on Diabetes Nephropathy

Med Sci Monit In Press; DOI: 10.12659/MSM.939482  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788


30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750